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Efecto del consumo del extracto de quinua en anemia ferropénica inducida en ratones
Effect of quinoa extract consumption on iron deficiency-induced anemia in mice
DOI:
https://doi.org/10.15446/rsap.v21n2.65311Keywords:
Quinoa, iron deficiency anemia, hemoglobin, albino mice strain BALB C. (es)Quinua, anemia ferropénica, hemoglobina, ratones BALB C. (en)
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Objetivos Determinar efecto del consumo del extracto de quinua en anemia ferropénica inducida, en ratones.
Material y Métodos Se utilizaron treinta ratones albinos M. musculus de la cepa Balb/c, machos de peso promedio 24±32,7 g. Se formó tres grupos de diez ratones cada uno: a) grupo control negativo hierro suficiente(HS),recibió 40g/d de alimento balanceado durante siete semanas; b)grupo control positivo hierro deficiente (HD), recibió 40g/d de dieta ferropénica durante siete semanas; y, c) grupo experimental hierro deficiente(HD), recibió 40g/d de dieta ferropénica durante siete semanas y a partir de la semana cinco se agregó 20g/d de extracto de quinua(EQ). Se midió el nivel de
hemoglobina.
Resultados Al finalizar el tratamiento, se observó diferencia significativa en los niveles de hemoglobina entre los grupos control positivo (8,9±1,1g/dL) HD y experimental (11,4±0,5 g/dL.) HD+EQ (t student, p<0,05). No se encontró diferencia significativa en los niveles de hemoglobina, al término del periodo de inducción entre los grupos control positivo (9,1±1,1) HD y experimental (9,3±0,7) HD (t student, p>0,05).
Conclusiones En condiciones experimentales, la quinua presenta efecto antianémico, sustentado en los resultados de los niveles de hemoglobina.
Objectives To determine the effect of quinoa extract consumption on iron deficiency-induced anemia in mice.
Materials and Methods Thirty male M. musculus albino mice of the Balb/c strain, with an average weight of 24±32.7 g, were used. Three groups of ten mice each were formed: 1) a negative control group of iron-sufficient (IS) mice that received 40g/d of balanced feed for 7 weeks; 2) a positive control group of iron-deficient (ID) mice that received 40g/d of feed rich in iron for 7 weeks; and 3) an experimental group of ID mice that received 40 g/d of feed rich in iron for 7 weeks and 20 g/d of quinoa extract (QE) from week 5. Hemoglobin levels were measured.
Results At the end of the treatment, a significant difference was found in hemoglobin levels between the positive (ID mice: 8.9±1.1 g/dL) and experimental (ID+QU mice
11.4±0.5 g/dL) groups (student's t, p<0.05). No significant difference was found in hemoglobin levels at the end of the induction period between the positive (IS mice: 9.1±1.1) and experimental (ID mice: 9.3±0.7) groups (student's t, p>0.05).
Conclusions Under experimental conditions, quinoa has an antianemic effect based on the results of hemoglobin levels.
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