Publicado

2022-09-01

BIOLOGICAL ACTIVITIES AND CHEMICAL COMPOSITION OF Rubia tinctorum (L) ROOT AND AERIAL PART EXTRACTS THEREOF

Actividades biológicas y composición química de los extractos de raíz y parte aérea de Rubia tinctorum L.

DOI:

https://doi.org/10.15446/abc.v27n3.95476

Palabras clave:

bioactivity, chemical composition, free radical, Rubia tinctorum L. (en)
bioactividad, composición química, radical libre, Rubia tinctorum L (es)

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In the present study, the phytochemical composition, antioxidant and anti-hemolytic activities of root and aerial part Rubia tinctorum hydromethanolic extracts were investigated. Phytochemical screening reveals the presence of phenol, alkaloids, coumarin, flavonoids, and tannins in both extracts. LC-ESI-MS/MS analysis showed the presence of 15 and 17 components in the root and the aerial part extracts, respectively. The quantitative analysis indicates the richness of root extracts in phenolic compounds (118.38 mg GAE/g) and flavonoids (45.29±0.04 mg GAE/g), the aerial part extract has the highest levels in tannins (134.1±0.1 mg GAE/g). Besides, aerial part extracts revealed the highest antioxidant activity for DPPH (83.23 %) and FRAP (1.51±0.22), while the root extract exhibited the highest potential for TAC and antihemolytic activity (61.09 %). Rubia tinctorum contains different active compounds to prevent diseases related to oxidative stress.

En el presente estudio se investigó la composición fitoquímica y las actividades antioxidante, y antihemolítica de los extractos hidrometanólicos de la raíz y la parte aérea de R. tinctorum. El cribado fitoquímico revela la presencia de fenol, alcaloides, cumarina, flavonoides y taninos en ambos extractos. El análisis LC-ESI-MS/MS mostró la presencia de 15 y 17 componentes en los extractos de la raíz y la parte aérea, respectivamente. El análisis cuantitativo indica la riqueza de los extractos de la raíz en compuestos fenólicos (118, 38 mg GAE/g) y flavonoides (45, 29±0, 04 mg GAE/g), el extracto de la parte aérea tiene los niveles más altos en taninos (134, 1±0, 1 mg GAE/g). Además, los extractos de la parte aérea revelaron la mayor actividad antioxidante para DPPH (83, 23 %) y FRAP (1, 51 ±0, 22), mientras que el extracto de la raíz exhibió el mayor potencial para TAC y actividad antihemolítica (61,09 %). Rubia tinctorum contiene diferentes compuestos activos para prevenir enfermedades relacionadas con el estrés oxidativo.

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APA

Houari, F. Z., Erenler, R. y Hariri, A. (2022). BIOLOGICAL ACTIVITIES AND CHEMICAL COMPOSITION OF Rubia tinctorum (L) ROOT AND AERIAL PART EXTRACTS THEREOF. Acta Biológica Colombiana, 27(3), 403–414. https://doi.org/10.15446/abc.v27n3.95476

ACM

[1]
Houari, F.Z., Erenler, R. y Hariri, A. 2022. BIOLOGICAL ACTIVITIES AND CHEMICAL COMPOSITION OF Rubia tinctorum (L) ROOT AND AERIAL PART EXTRACTS THEREOF. Acta Biológica Colombiana. 27, 3 (sep. 2022), 403–414. DOI:https://doi.org/10.15446/abc.v27n3.95476.

ACS

(1)
Houari, F. Z.; Erenler, R.; Hariri, A. BIOLOGICAL ACTIVITIES AND CHEMICAL COMPOSITION OF Rubia tinctorum (L) ROOT AND AERIAL PART EXTRACTS THEREOF. Acta biol. Colomb. 2022, 27, 403-414.

ABNT

HOUARI, F. Z.; ERENLER, R.; HARIRI, A. BIOLOGICAL ACTIVITIES AND CHEMICAL COMPOSITION OF Rubia tinctorum (L) ROOT AND AERIAL PART EXTRACTS THEREOF. Acta Biológica Colombiana, [S. l.], v. 27, n. 3, p. 403–414, 2022. DOI: 10.15446/abc.v27n3.95476. Disponível em: https://revistas.unal.edu.co/index.php/actabiol/article/view/95476. Acesso em: 29 mar. 2024.

Chicago

Houari, Fatima Zohra, Ramazan Erenler, y Ahmed Hariri. 2022. «BIOLOGICAL ACTIVITIES AND CHEMICAL COMPOSITION OF Rubia tinctorum (L) ROOT AND AERIAL PART EXTRACTS THEREOF». Acta Biológica Colombiana 27 (3):403-14. https://doi.org/10.15446/abc.v27n3.95476.

Harvard

Houari, F. Z., Erenler, R. y Hariri, A. (2022) «BIOLOGICAL ACTIVITIES AND CHEMICAL COMPOSITION OF Rubia tinctorum (L) ROOT AND AERIAL PART EXTRACTS THEREOF», Acta Biológica Colombiana, 27(3), pp. 403–414. doi: 10.15446/abc.v27n3.95476.

IEEE

[1]
F. Z. Houari, R. Erenler, y A. Hariri, «BIOLOGICAL ACTIVITIES AND CHEMICAL COMPOSITION OF Rubia tinctorum (L) ROOT AND AERIAL PART EXTRACTS THEREOF», Acta biol. Colomb., vol. 27, n.º 3, pp. 403–414, sep. 2022.

MLA

Houari, F. Z., R. Erenler, y A. Hariri. «BIOLOGICAL ACTIVITIES AND CHEMICAL COMPOSITION OF Rubia tinctorum (L) ROOT AND AERIAL PART EXTRACTS THEREOF». Acta Biológica Colombiana, vol. 27, n.º 3, septiembre de 2022, pp. 403-14, doi:10.15446/abc.v27n3.95476.

Turabian

Houari, Fatima Zohra, Ramazan Erenler, y Ahmed Hariri. «BIOLOGICAL ACTIVITIES AND CHEMICAL COMPOSITION OF Rubia tinctorum (L) ROOT AND AERIAL PART EXTRACTS THEREOF». Acta Biológica Colombiana 27, no. 3 (septiembre 1, 2022): 403–414. Accedido marzo 29, 2024. https://revistas.unal.edu.co/index.php/actabiol/article/view/95476.

Vancouver

1.
Houari FZ, Erenler R, Hariri A. BIOLOGICAL ACTIVITIES AND CHEMICAL COMPOSITION OF Rubia tinctorum (L) ROOT AND AERIAL PART EXTRACTS THEREOF. Acta biol. Colomb. [Internet]. 1 de septiembre de 2022 [citado 29 de marzo de 2024];27(3):403-14. Disponible en: https://revistas.unal.edu.co/index.php/actabiol/article/view/95476

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