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Equivalence of grain and forage composition in corn hybrid (Zea mays L.) from genetically modified off-patent (event TC1507) and non-genetically modified conventional corn
Equivalencia de la composición del grano y del forraje en el híbrido de maíz (Zea mays L.) modificado genéticamente off-patent (evento TC1507) y en el maíz convencional no modificado genéticamente
DOI:
https://doi.org/10.15446/agron.colomb.v40n2.98948Keywords:
transgenic corn, genetically modified off-patent crops, substantial equivalence, food safety, compositional analysis (en)maíz transgénico, cultivos transgénicos off-patent, equivalencia sustancial, inocuidad de los alimentos, análisis composicional (es)
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Off-patent corn (event TC1507) contains genes coding for CRY1F and PAT proteins, which confer resistance to lepidopteran insects and tolerance to the herbicide glufosinate-ammonium. We employed the substantial equivalence approach to investigate the compositional safety of the corn off-patent event (TC1507). The levels of the nutritional contents of proximate analytes in grain and forage tissues of off-patent genotypes of transgenic maize plants and conventional corn genotypes were compared. The levels of the analytes evaluated in the transgenic plants were found to be within the ranges published in the literature for non-transgenic corn and were statistically indistinguishable from the conventional corn from which they are derived (elite corn lines), indicating substantial equivalence between the off-patent (event TC1507) and its conventional counterpart. These results constitute key evidence of the safety evaluation of the world’s first transgenic corn developed from technologies that are in the public domain.
El maíz off-patent (evento TC1507) contiene los genes que codifican para las proteínas CRY1F y PAT que le confieren resistencia a insectos lepidópteros y tolerancia al herbicida glufosinato de amonio. Empleamos el enfoque de equivalencia sustancial para investigar la seguridad composicional del maíz off-patent (evento TC1507). Se realizaron comparaciones de los contenidos nutricionales de los analitos proximales en los tejidos de grano y forraje de los genotipos off-patent de plantas de maíz transgénicas y de los genotipos de maíz convencional. Los niveles de los analitos evaluados en las plantas transgénicas se encontraron dentro de los rangos publicados en la literatura para el maíz no transgénico y fueron estadísticamente indistinguibles del maíz convencional del cual derivan (líneas elite de maíz), lo que indica la equivalencia sustancial entre el off-patent (evento TC1507) y su homólogo convencional. Estos resultados constituyen una evidencia clave de la evaluación de seguridad del primer maíz transgénico en el mundo desarrollado con base en tecnologías que están en dominio público.
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