One Health and Engineering: using engineering to further pave the roadmap towards global health security, pandemic preparedness, and personalized medicine
This article delves into the intricate interplay among human, animal, and environmental health, acknowledging the convergence of knowledge across diverse disciplines where traditional boundaries blur, fostering remarkable advancements in engineering, genomics, and medicine. The One Health framework transcends mere disease control, aspiring to enhance the well-being of all life forms on Earth. Positioned uniquely to address global health challenges, pandemics, and personalized medicine, this holistic approach identifies pressing issues such as pandemic preparedness, antimicrobial resistance, zoonotic disease surveillance, vaccine equity, climate change's health impacts, food safety, vector-borne diseases, healthcare access equity, data integration, and public awareness and education. It emphasizes the driving forces behind these challenges, encompassing demographic shifts, urbanization, migration, gender-based violence, poverty, globalization, and climate change. Most notably, we delineate One Health and Engineering (OHE) as a pioneering discipline harmoniously blending engineering, life sciences, and environmental sciences to address multifaceted health challenges. Engineers play a pivotal role in crafting innovative solutions through technology, data-driven methodologies, and sustainable infrastructure. The genomics' integration and data science into personalized medicine represents a transformative approach to disease prevention and healthcare delivery. Insights into One Health and Engineering initiatives in Colombia highlight the profound significance of interdisciplinary collaboration in addressing the intricate web of health, environmental, and societal challenges. We showcase the collaborative efforts between the Universidad Nacional de Colombia and the University of Wisconsin-Madison in the establishment of the One Health Genomic Laboratory in Medellín, a beacon of research into diseases, pathogen discovery, and pandemic preparedness
Referencias
Schneider, M.C., Munoz-Zanzi, C., Kyung-duk, M., and Aldighieri, S.,“One Health” from concept to application in the global world, from: Global Public Health, DOI: https://doi.org/10.1093/acrefore/9780190632366.013.29.
CDC, One Health, [online]. [last accessed in October, 2023.]. Available at: https://www.cdc.gov/onehealth/index.html,
Ryu, S. Kim, B.I., Lim, J.S., Tan, C.S., and Chun, B.C., One Health perspectives on emerging public health threats. J. Prev. Med. Public Health. 50(6), pp. 411-414, 2017. DOI: https://doi.org/10.3961/jpmph.17.097
Naddeo, V., One planet, one health, one future: THE environmental perspective. Water Environ Res. 93(9), pp. 1472-1475, 2021 DOI: https://doi.org/10.1002/wer.1624.
Buchholz, K., Unsafe water kills more people than disasters and conflicts, [online]. 2022. [last accessed in October 2023]. Available at: https://www.statista.com/chart/17445/global-access-to-safe-drinking-water/,
Mongabay, Eight of the 10 nations most at risk from climate change and toxic pollution are in Africa, [online]. 2021. [last accessed in October, 2023]. Available at: https://earth.org/nations-most-at-risk-from-climate-change-and-toxic-pollution-in-africa/.
Igini, M., World Food Day 2023: Why global food security matters in [online]. 2023. [last accessed in October, 2023]. Available at: https://earth.org/global-food-security/
Helmy, M., Awad, M., and Mosa, K.A., Limited resources of genome sequencing in developing countries: Challenges and solutions. Applied & Translational Genomics 9, pp. 15-19, 2016. DOI: https://doi.org/10.1016/j.atg.2016.03.003
Roser, M., and Ritchie, H., HIV/AIDS, Our World in Data. [online]. 2018. [last accessed in October, 2023]. Available at: https://ourworldindata.org/hiv-aids
Capote-Negrin, L.G., Epidemiology of cervical cancer in Latin America. Ecancer, 9, art. 577, 2015. DOI: https://doi.org/10.3332/ecancer.2015.577
Bruni, L., Diaz, M., Castellsagué, X., Ferrer, E., Bosch, F.X., and de Sanjosé, S., Cervical human papillomavirus prevalence in 5 continents: meta-analysis of 1 million women with normal cytological findings. J Infect 202(12), pp. 1789-1799, 2010. DOI: https://doi.org/10.1086/657321
Carlson, C.J., and Phelan, A.L., International law reform for One Health notifications. Lancet. 400(10350), pp. 462-468, 2022. DOI: https://doi.org/10.1016/S0140-6736(22)00942-4.
Standley, C., Boyce, M.R., Klineberg, A., Essix, G., and Katz, R., Organization of oversight for integrated control of neglected tropical diseases within Ministries of Health. PLoS Negl Trop Dis 12(11), art. e0006929, 2018. DOI: https://doi.org/10.1371/journal.pntd.0006929
McEwen, S.A., and Collignon, P.J., Antimicrobial resistance: a one health perspective. Microbiol Spectr. 6(2), 2018. DOI: https://doi.org/10.1128/microbiolspec
Sinclair, J.R., Importance of a One Health approach in advancing global health security and the Sustainable Development Goals. Rev Sci Tech. 38(1), pp. 145-154, 2019. DOI: https://doi.org/10.20506/rst.38.1.2949.
Zinsstag, J., Crump, L., Schelling, E., Hattendorf, J., Maidane, Y.O., Ali, K.O., Muhummed, A., Umer, A.A., Aliyi, F., Nooh, F., Abdikadir, M.I., Ali, S.M., Hartinger, S., Mäusezahl, D., de White, M.B.G., Cordon-Rosales, C., Castillo, D.A., McCracken, J., Abakar, F., Cercamondi, C., Emmenegger, S., Maier, E., Karanja, S., Bolon, I., de Castañeda, R.R., Bonfoh, B., Tschopp, R., Probst-Hensch, N., and Cissé, G., Climate change and One Health. FEMS Microbiol Lett., 365(11), art. fny085, 2018. DOI: https://doi.org/10.1093/femsle/fny085.
van Herten, J., Bovenkerk, B., and Verweij, M., One Health as a moral dilemma: towards a socially responsible zoonotic disease control. Zoonoses Public Health. 66(1), pp. 26-34, 2019. DOI: https://doi.org/10.1111/zph.12536.
Urban, L., Perlas, A., Francino, O., Martí-Carreras, J., Muga, B.A., Mwangi, J.W., Boykin-Okalebo, L., Stanton, J.L., Black, A., Waipara, N., Fontsere, C., Eccles, D., Urel, H., Reska, T., Morales, H.E., Palmada-Flores, M., Marques-Bonet, T., Watsa, M., Libke, Z., Erkenswick, G., and van Oosterhout, C., Real-time genomics for One Health. Mol Syst Biol. 19(8), art. e11686. 2023. DOI: https://doi.org/10.15252/msb.202311686
Teague, B., Waterman, M.S., Goldstein, S., et al., High-resolution human genome structure by single-molecule analysis. Proc National Acad Sci. 107(24), pp. 10848-10853, 2010. DOI: https://doi.org/10.1073/pnas.0914638107
Fuller, C.W., Middendorf, L.R., Benner, S.A., et al., The challenges of sequencing by synthesis. Nat Biotechnol. 27(11), pp. 1013-1023, 2009. DOI: https://doi.org/10.1038/nbt.1585.
Valouev, A., Zhang, Y., Schwartz, D.C., and Waterman, M.S., Refinement of optical map assemblies. Bioinformatics. 22(10), pp. 1217-1224, 2006. DOI: https://doi.org/10.1093/bioinformatics/btl063
Mercado-Reyes, M., Malagón-Rojas, J., Rodríguez-Barraquer, I., et al., Seroprevalence of anti-SARS-CoV-2 antibodies in Colombia, 2020: a population-based study. Lancet Regional Heal Am. 9, pp. 100195-100195, 2022. DOI: https://doi.org/10.1016/j.lana.2022.100195
Orf, G.S., Pérez, L.J., Ciuoderis, K., et al., The Principles of SARS-CoV-2 Intervariant Competition Are Exemplified in the Pre-Omicron Era of the Colombian Epidemic. Microbiology Spectrum, 11(3), art. e05346-22, 2023. DOI: https://doi.org/10.1128/spectrum.05346-22.
Hernandez-Ortiz, J., Cardona, A., Ciuoderis, K., et al., Assessment of SARS-CoV-2 Mu Variant Emergence and Spread in Colombia. Jama Netw Open. 5(3), art. e224754, 2022. DOI: https://doi.org/10.1001/jamanetworkopen.2022.4754
Laiton-Donato, K., Franco-Muñoz, C., Álvarez-Díaz, D.A., et al., Characterization of the emerging B.1.621 variant of interest of SARS-CoV-2. Infect Genetics Evol. 95, art. 105038, 2021. DOI: https://doi.org/10.1016/j.meegid.2021.105038
Halfmann, P.J., Iida, S., Iwatsuki-Horimoto, K., et al., SARS-CoV-2 Omicron virus causes attenuated disease in mice and hamsters. Nature. 603(7902), pp. 687-692, 2022. DOI: https://doi.org/10.1038/s41586-022-04441-6
Ciuoderis, K.A., Berg, M.G., Perez, L.J., et al., Oropouche virus as an emerging cause of acute febrile illness in Colombia. Emerg Microbes Infect. 11(1), pp. 2645-2657, 2022. DOI: https://doi.org/10.1080/22221751.2022.2136536.
Ciuoderis, K.A., Usuga, J., Moreno, I., et al., Characterization of dengue virus serotype 2 cosmopolitan genotype circulating in Colombia. The American Journal of Tropical Medicine and Hygiene. Published online October 09th, 2023. DOI: https://doi.org/10.4269/ajtmh.23-0375
Dahmer, K.J., Palma-Cuero, M., Ciuoderis, K., et al., Molecular surveillance detects high prevalence of the neglected parasite Mansonella ozzardi in the Colombian Amazon. J Infect Dis. Published online 2023. DOI: https://doi.org/10.1093/infdis/jiad331
Averhoff, F., Berg, M., Rodgers, M., et al., The abbott pandemic defense coalition: a unique multisector approach adds to global pandemic preparedness efforts. Int J Infect Dis. 117, pp. 356-360, 2022. DOI: https://doi.org/10.1016/j.ijid.2022.02.001
Cómo citar
IEEE
ACM
ACS
APA
ABNT
Chicago
Harvard
MLA
Turabian
Vancouver
Descargar cita
CrossRef Cited-by
1. Rita Elizabeth Velastegui-Hernández, Verónica Gabriela Salinas-Velastegui, Diana Catalina Velastegui-Hernandez, Estefania Araceli Reyes-Rosero, Andrea Carolina Cevallos-Teneda, Andrea Alexandra Tufiño-Aguilar, Fabricio Alejandro Vasquez de la Bandera, Gabriela Sandoval, Luis Felipe Contreras-Vásquez, Luis Fabián Salazar-Garcés. (2025). AI in the development of vaccines for emerging and re-emerging diseases. Salud, Ciencia y Tecnología, 4 https://doi.org/10.56294/saludcyt2024.1285.
2. Siddig Ibrahim Abdelwahab, Manal Mohamed Elhassan Taha, Khaled A. Sahli, Ahmad Assiri, Marwa Qadri, Abdulaziz Alarifi, Amani Khardali, Abdullah Farasani, Saleh M. Abdullah, Mohammed Jeraiby, Nizar A. Khamjan, Jobran M. Moshi, Khloud H. Alsaadi, Saeed Alshahrani, Hussam M. Shubaily, Abdulwahab Zaid Binjomah. (2026). Mapping the evolution of one health research (1981–2025). Journal of Public Health, https://doi.org/10.1007/s10389-026-02686-3.
Dimensions
PlumX
Visitas a la página del resumen del artículo
Descargas
Licencia
Derechos de autor 2023 DYNA

Esta obra está bajo una licencia internacional Creative Commons Atribución-NoComercial-SinDerivadas 4.0.
El autor o autores de un artículo aceptado para publicación en cualquiera de las revistas editadas por la facultad de Minas cederán la totalidad de los derechos patrimoniales a la Universidad Nacional de Colombia de manera gratuita, dentro de los cuáles se incluyen: el derecho a editar, publicar, reproducir y distribuir tanto en medios impresos como digitales, además de incluir en artículo en índices internacionales y/o bases de datos, de igual manera, se faculta a la editorial para utilizar las imágenes, tablas y/o cualquier material gráfico presentado en el artículo para el diseño de carátulas o posters de la misma revista.




