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Fucoxanthin from marine microalga Isochrysis galbana: optimization of extraction methods with organic solvents
Fucoxantina desde la microalga Isochrysis galbana: optimización de métodos de extracción con solventes orgánicos
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https://doi.org/10.15446/dyna.v86n210.72932Palabras clave:
Isochrysis galbana, carotenoids, bioactive compounds, extraction solvents, extraction time (en)Isochrysis galbana, carotenoides, compuestos bioactivos, solventes de extracción, tiempo de extracción (es)
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Fucoxanthin was the carotenoid studied from the marine microalga Isochrysis galbana for its importance in preventing obesity and diabetes. In this manner, seven solvents were used to fucoxanthin extraction, highlighting methanol and ethanol with 6.282 and 4.187 mg/g, respectively. However, petroleum ether and n-hexane were the worst solvents for fucoxanthin extraction, obtaining approximately 12-folds less content. Extraction time was another relevant parameter in improve fucoxanthin extraction where 10 min was the best time reaching 7.464 mg/g under 100% ethanol. Finally, we propose the use of I. galbana as natural source of fucoxanthin, a bioactive compound useful
for food industry.
Fucoxantina fue el carotenoide estudiado desde la microalga marina Isochrysis galbana por su importancia en la prevención de la obesidad y la diabetes. De esta manera, siete solventes fueron usados para extraer fucoxantina destacando metanol y etanol con 6.282 and 4.187 mg/g, respectivamente. Sin embargo, éter de petróleo y n-hexano fueron los peores solventes para la extracción de fucoxantina, obteniendo
aproximadamente 12 veces menos contenido. El tiempo de extracción fue otro parámetro relevante para mejorar la extracción de fucoxantina, donde 10 minutos fue el mejor tiempo para alcanzar 7.464 mg / g con 100% etanol. Finalmente, proponemos el uso de I. galbana como fuente natural de fucoxantina, un compuesto bioactivo útil para la industria alimentaria.
Referencias
Poojary, M.M., Barba, F. J., Aliakbarian, B., Donsì, F., Pataro, G., Dias, D.A., & Juliano, P. Innovative alternative technologies to extract carotenoids from microalgae and seaweeds. Mar Drugs, 14 (11), pp. 214, 2016. DOI: 10.3390/md14110214
Raposo, M.F.D.J., de Morais, A.M.M.B., & de Morais, R.M.S.C. Carotenoids from marine microalgae: A valuable natural source for the prevention of chronic diseases. Mar Drugs, 13 (8), pp. 5128-5155, 2015. DOI: 10.3390/md13085128
Goodwin, T.W. Nature and distribution of carotenoids. Food Chem, 5 (1), pp. 3-13, 1980. DOI: 10.1016/0308-8146(80)90061-8.
Kushwaha, K., Saini, A., Saraswat, P., Agarwal, M.K., & Saxena, J. Colorful World of Microbes: Carotenoids and Their Applications. Adv Biol, Article ID 837891, pp. 13, 2014. DOI: 10.1155/2014/837891.
Kumar, R., Hariram, S., & Won, S. Carotenoids from fruits and vegetables: Chemistry, analysis, occurrence, bioavailability and biological activities. Food Res Int, 76 (3), pp. 735–750, 2015. DOI: 10.1016/j.foodres.2015.07.047
Telfer, A., Pascal, A., & Gall, A. Carotenoids in photosynthesis. In Carotenoids (pp. 265-308), 2008. Birkhäuser Basel. DOI:10.1007/978-3-7643-7499-0_14
Frank, H.A., & Cogdell, R.J. Carotenoids in photosynthesis. Photochem photobiol, 63 (3), pp. 257-264, 1996. DOI: 10.1111/j.1751-1097.1996.tb03022.x
Miyashita, K., Nishikawa, S., Beppu, F., Tsukui, T., Abe, M., & Hosokawa, M. The allenic carotenoid fucoxanthin, a novel marine nutraceutical from brown seaweeds. J Sci Food Agr, 91 (7), pp. 1166-1174, 2011. DOI: 10.1002/jsfa.4353
Valdés, Y.A., & Soto, M.F.B. Algas, aliadas en el pasado y sustento para el futuro. Tecnol Química, 28 (3), pp. 46-50, 2017. ISSN: 0041-8420
Saini, R.K., & Keum, Y.S. Carotenoid extraction methods: A review of recent developments. Food Chem, 240, pp. 90-103, 2018. DOI: 10.1016/j.foodchem.2017.07.099
Kim, S.M., Kang, S.W., Kwon, O.N., Chung, D., & Pan, C.H. Fucoxanthin as a major carotenoid in Isochrysis aff. galbana: Characterization of extraction for commercial application. J Korean Soc Appl Bi, 55 (4), pp. 477-483, 2012. DOI: 10.1007/s13765-012-2108-3
Woo, M.N., Jeon, S.M., Shin, Y.C., Lee, M.K., Kang, M., & Choi, M.S. Anti‐obese property of fucoxanthin is partly mediated by altering lipid‐regulating enzymes and uncoupling proteins of visceral adipose tissue in mice. Mol Nutr Food Res, 53 (12), pp. 1603-1611, 2009. DOI: 10.1002/mnfr.200900079
Peng, J., Yuan, J.P., Wu, C.F., & Wang, J.H. Fucoxanthin, a marine carotenoid present in brown seaweeds and diatoms: metabolism and bioactivities relevant to human health. Mar Drugs, 9 (10), pp. 1806–1828, 2011. DOI: 10.3390/md9101806.
Wu, S., Xie, X., Huan, L., Zheng, Z., Zhao, P., Kuang, J., & Wang, G. Selection of optimal flocculant for effective harvesting of the fucoxanthin-rich marine microalga Isochrysis galbana. J Appl Phycol, 28 (3), pp. 1579-1588, 2016. DOI: 10.1007/s10811-015-0716-0
Tokuşoglu, Ö., & Üunal, M. Biomass nutrient profiles of three microalgae: Spirulina platensis, Chlorella vulgaris, and Isochrisis galbana. J Food Sci, 68 (4), pp. 1144-1148, 2003. DOI: 10.1111/j.1365-2621.2003.tb09615.x
Kim, S.M., Jung, Y.J., Kwon, O.N., Cha, K.H., Um, B.H., Chung, D., & Pan, C.H. A potential commercial source of fucoxanthin extracted from the microalga Phaeodactylum tricornutum. Appl Biochem Biotech, 166 (7), pp. 1843–55, 2012. DOI: 10.1007/s12010-012-9602-2
Rijstenbil, J.W. Effects of UVB radiation and salt stress on growth, pigments and antioxidative defence of the marine diatom Cylindrotheca closterium. Mar Ecol Prog Ser, 254, pp. 37–48, 2003. DOI: 10.3354/meps254037
Yen, H.W., Yang, S.C., Chen, C.H., Jesisca, & Chang, J.S. Supercritical fluid extraction of valuable compounds from microalgal biomass. Bioresource Technol, 184: pp. 291–296, 2015. DOI: 10.1016/j.biortech.2014.10.030.
Alfonsi, K., Colberg, J., Dunn, P. J., Fevig, T., Jennings, S., Johnson, T. A., Kleine, H.P., Knight, C., Nagy, M.A., Perry, D.A., Stefaniak, M. Green chemistry tools to influence a medicinal chemistry and research chemistry based organisation. Green Chem, 10 (1), pp. 31–36, 2008. DOI: 10.1039/B711717E.
Capello, C., Fischer, U., & Hungerbühler, K. What is a green solvent? A comprehensive framework for the environmental assessment of solvents. Green Chem, 9 (9), pp. 927–934, 2007. DOI: 10.1039/B617536H
Castro-Puyana, M., Herrero, M., Urreta, I., Mendiola, J. A., Cifuentes, A., Ibáñez, E., & Suárez-Alvarez, S. Optimization of clean extraction methods to isolate carotenoids from the microalga Neochloris oleoabundans and subsequent chemical characterization using liquid chromatography tandem mass spectrometry. Anal Bioanal Chem, 405 (13), pp. 4607-4616, 2013. DOI: 10.1007/s00216-012-6687-y
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8. Mary Kate M. Lane, Elise B. Gilcher, Melissa M. Ahrens-Víquez, Rachel S. Pontious, Nora E. Wyrtzen, Julie B. Zimmerman. (2024). Elucidating supercritical fluid extraction of fucoxanthin from algae to enable the integrated biorefinery. Bioresource Technology, 406, p.131036. https://doi.org/10.1016/j.biortech.2024.131036.
9. F. Gholamian, N. Karimi, F. Gholamian, P. Bayat. (2023). The effects of some detergents and heavy metals on fucoxanthin yield and phycoremediation potential of Polycladia myrica. International Journal of Environmental Science and Technology, 20(8), p.8349. https://doi.org/10.1007/s13762-023-05005-5.
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13. K. Anjana, K. Arunkumar. (2024). Brown algae biomass for fucoxanthin, fucoidan and alginate; update review on structure, biosynthesis, biological activities and extraction valorisation. International Journal of Biological Macromolecules, 280, p.135632. https://doi.org/10.1016/j.ijbiomac.2024.135632.
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15. Farah Hadjkacem, Jihen Elleuch, Guillaume Pierre, Imen Fendri, Philippe Michaud, Slim Abdelkafi. (2024). Production and purification of fucoxanthins and β-carotenes from Halopteris scoparia and their effects on digestive enzymes and harmful bacteria . Environmental Technology, 45(15), p.2923. https://doi.org/10.1080/09593330.2023.2195562.
16. Micaela de Bon, Mauricio Rodríguez Chialanza, María Fernanda Cerdá. (2022). Fucoxanthin from the Antarctic Himantothallus grandifollius as a sensitizer in DSSC. Journal of the Iranian Chemical Society, 19(8), p.3627. https://doi.org/10.1007/s13738-022-02560-5.
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