Publicado

2021-07-28

Influence of porosity on the biomimetic growing patterns of bonelike apatite on the surface of calcium phosphate – calcium titanate – alumina compounds

Influencia de la porosidad en el patrón de crecimiento biomimético de apatita tipo hueso en la superficie de compuestos de fosfato de calcio – titanato de calcio - alúmina

DOI:

https://doi.org/10.15446/dyna.v88n218.91651

Palabras clave:

Biomedical applications, Sintering, Porosity, Growing pattern. (en)
aplicaciones biomédicas;, sinterización;, porosidad;, patrón de crecimiento (es)

Autores/as

Biomaterials are increasingly used for bone tissue regeneration because of their potential to overcome the morbidity caused by autologous bone grafts and allografts. A combination of properties is required, as biocompatibility, osteoconductivity, good mechanical strength and fracture toughness. In this research, a compound of alumina matrix with calcium titanate and calcium phosphate is proposed. Magnesium stearate was used as porogen agent. The aim of this research was to evaluate the effect of porosity on the crystalline phases formed, as well as the growing pattern and types of calcium phosphates formed after soaking in Hanks’ solution. It was found that the resultant porosity does affect the crystalline phases formed after sintering. It was also found that hydroxyapatite and octacalcium phosphate precipitates after soaking in Hank’s solution, and that the porosity affects the growing pattern.

Los biomateriales se usan ampliamente en regeneración de tejidos debido a su gran potencial para superar la morbilidad causada por injertos y aloinjertos óseos autólogos. En esta aplicación se requiere una combinación de propiedades importantes, tales como biocompatiblidad, osteoconductividad, buena resistencia mecánica y tenacidad a la fractura. En esta investigación se propone el uso de compuestos ricos en alúmina con titanato de calcio y fosfato de calcio. Como agente porógeno se utilizó estearato de magnesio. El objetivo fue evaluar el efecto de la porosidad en las fases cristalinas formadas, así como en el patrón de crecimiento y tipos de fosfatos formados después de inmersión en solución de Hank. Se encontró que la porosidad resultante afecta el tipo de fases cristalinas formadas después de la sinterización. También se encontró que después de la inmersión en solución de Hank precipitan hidroxiapatita y fosfato octocálcico, y que la porosidad afecta el patrón de crecimiento de ambas fases.

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[1]
“Influencia de la porosidad en el patrón de crecimiento biomimético de apatita tipo hueso en la superficie de compuestos de fosfato de calcio – titanato de calcio - alúmina”, DYNA, vol. 88, no. 218, pp. 24–33, Jul. 2021, doi: 10.15446/dyna.v88n218.91651.