REGENERACIÓN DEL ÓRGANO CUTÁNEO MEDIANTE INGENIERÍA DE TEJIDOS
CUTANEOUS ORGAN REGENERATION BY VIRTUE OF TISSUE ENGINEERING
DOI:
https://doi.org/10.15446/mo.n60.82752Keywords:
Ingeniería de tejidos, regeneración, polímeros, biocompatibilidad (es)Tissue engineering, skin, cutaneous organ, regeneration, biocompatible polymers (en)
Downloads
La ingeniería de tejidos es una ciencia que busca desarrollar sustitutos de tejido y órganos para mantener, restaurar o aumentar las funciones de sus contrapartes heridas o enfermas in vivo. El órgano cutáneo es el tejido que constituye la mayor extensión en el cuerpo humano, y a la vez es el órgano más externo, lo cual, consecuentemente, hace que sea el órgano más propenso a herirse. Debido a esta problemática las investigaciones y esfuerzos con fines de solucionar este problema son constantes. El enfoque de la revisión es el de presentar métodos recientes a través de los cuales la ingeniería de tejidos, utilizando compuestos biocompatibles, ha logrado una satisfactoria regeneración del órgano cutáneo, esto incluirá la revisión del uso de métodos para la regeneración de tejidos, tales como la impresión 3D y el uso de andamios poliméricos, apósitos biodiseñados y células madre.
Tissue engineering's inherent purpose is to develop skin and organ substitutes to sustain, restore or enhance wounded or sick skin functions in vivo. The cutaneous organ tissue makes up the largest organ extension within the human body, and it is also the most outward organ, which makes it the most prone to injury. Due to these problems, constant effort and research has been made looking to solve them. The review's focus is to present recent methods through which tissue engineering, using biocompatible compounds, has achieved a successful cutaneous organ healing. This will include the review of tissue engineering methods such as 3D printing and the usage of a polymeric scaffold, wound dressings and stem cells.
References
K. Vig, A. Chaudhari, S. Tripathi, S. Dixit, R. Sahu, S. Pillai, V. A. Dennis, and S. R. Singh, Int. J. Mol. Sci. 18, 789 (2017).
R. F. Pereira, C. C. Barrias, C. C, P. L. Granja, and P. J. Bartolo, Nanomedicine 8, 603 (2013).
A. A. Chaudhari, K. Vig, D. R. Baganizi, R. Sahu, S. Dixit, V. Dennis, S. R. Singh, and S. R. Pillai, Int. J. Mol. Sci. 17, 1974 (2016).
L. T. Beringer, S. Li, E. J. Kallick, K. J. Shields, E. M. Faight, F. Cartieri, A. Aballay, H. Edington, and S. Averick, Ind. Eng. Chem. Res. 55, 12687 (2016).
M. Sheikholeslam, M. E. E. Wright, M. G. Jeschke, and S. Amini-Nik, Advanced Healthcare Materials 7, 1700897 (2017).
A. Khademhosseini and R. Langer, Nat. Protoc. 11, 1775 (2016).
F.-M. Chen and X. Liu, Progress in Polymer Science 53, 86 (2016).
P. Goodarzi, K. Falahzadeh, M. Nematizadeh, P. Farazandeh, M. Payab, B. Larijani, A. T. Beik, and B. Arjmand, Cell Biology and Translational Medicine 3, 143 (2018).
R. Wong, S. Geyer, W. Weninger, J.-C. Guimberteau, and J. K. Wong, Experimental Dermatology 25, 92 (2016).
K. Kabashima, T. Honda, F. Ginhoux, and G. Egawa, Nature Reviews Immunology 19, 19 (2019).
Y. Gilaberte, L. Prieto-Torres, I. Pastushenko, and Juarranz, in Nanoscience in Dermatology, edited by M. R. Hamblin, P. Avci, and T. W. Prow (Academic Press, Boston, 2016) pp. 1 -14.
J. Boateng and O. Catanzano, J. Pharm. Sci. 104, 3653 (2015).
M. Takeo, W. Lee, and M. Ito, Cold Spring Harb. Perspect. Med. 32 (2015).
M. P. Caley, V. L. Martins, and E. A. O'Toole, Advances in Wound Care 4, 225 (2015).
M. H. Periayah, A. S. Halim, and A. Z. M. Saad, Int J Hematol Oncol Stem Cell Res. 11, 319 (2017).
A. C. Gonzalez, T. F. Costa, Z. de Araújo Andrade, and A. R. Medrado, An. Bras. Dermatol. 91, 614 (2016).
M. Sinha, C. K. Sen, K. Singh, A. Das, S. Ghatak, B. Rhea, B. Blackstone, H. M. Powell, S. Khanna, and S. Roy, Nat Commun 9, 936 (2018).
U. Jammalamadaka and K. Tappa, J. Funct. Biomater. 9, 22 (2018).
H. Xu, Z. Fang, W. Tian, Y. Wang, Q. Ye, L. Zhang, and J. Cai, Adv. Mater. 30, 1801100 (2018).
M. Mir, M. N. Ali, A. Barakullah, A. Gulzar, M. Arshad, S. Fatima, and M. Asad, Prog. Biomater. 7, 1 (2018).
X. Li, X. Ye, J. Qi, R. Fan, X. Gao, Y. Wu, L. Zhou, A. Tong, and G. Guo, Int. J. of Nanomedicine 11, 3993 (2016).
T. H. Qazi, D. J. Mooney, M. Pumberger, S. Geissler, and G. N. Duda, Biomaterials 53, 502 (2015).
A. Dobreikina, T. Shklyar, A. Safronov, and F. Blyakhman, Polymer International 67, 1330 (2018).
N. Cubo, M. Garcia, J. F. del Ca~nizo, D. Velasco, and J. L. Jorcano, Biofabrication 9, 015006 (2016).
J. An, J. E. M. Teoh, R. Suntornnond, and C. K. Chua, Engineering 1, 261 (2015).
W. L. Ng, W. Y. Yeong, and M. W. Naing, Int. J. Bioprinting 2, 53 (2016).
E. S. Bishop, S. Mostafa, M. Pakvasa, H. H. Luu, M. J. Lee, J. M. Wolf, G. A. Ameer, T.-C. He, and R. R. Reid, Genes Diseases 4, 185 (2017).
D. Singh, D. Singh, and S. S. Han, Polymers 8, 19 (2016).
P. He, J. Zhao, J. Zhang, B. Li, Z. Gou, M. Gou, and X. Li, Burns & trauma 6, 5 (2018).
S. Derakhshanfar, R. Mbeleck, K. Xu, X. Zhang, W. Zhong, and M. Xing, Bioact. Mater. 3, 144 (2018).
M. Rimann, E. Bono, H. Annaheim, M. Bleisch, and U. Graf-Hausner, J. Lab. Autom. 21, 496 (2016).
A. Rees, L. C. Powell, G. Chinga-Carrasco, D. T. Gethin, K. Syverud, K. E. Hill, and D. W. Thomas, BioMed Research International 2015, 7 (2015).
Z. Wu, X. Su, Y. Xu, B. Kong, W. Sun, and S. Mi, Sci. Rep. 6, 24474 (2016).
Z. Wang, R. Abdulla, B. Parker, R. Samanipour, S. Ghosh, and K. Kim, Biofabrication 7, 045009 (2015).
X. Zhao, Q. Lang, L. Yildirimer, Z. Y. Lin, W. Cui, N. Annabi, K. W. Ng, M. R. Dokmeci, A. M. Ghaemmaghami, and A. Khademhosseini, Adv. Healthc. Mater. 5, 108 (2016).
G. Rath, T. Hussain, G. Chauhan, T. Garg, and A. K. Goyal, J. Drug Target. 24, 520 (2016).
R. Y. Basha, T. S. Sampath Kumar, and M. Doble, Macromol. Mater. Eng. 302, 1600417 (2017).
S. Deepthi, C. V. S. Viha, C. Thitirat, T. Furuike, H. Tamura, and R. Jayakumar, Polymers 6, 2974 (2014).
A. Oryan and S. Sahvieh, Int. J. Biol. Macromol. 104, 1003 (2017).
M. Eskandarlou, M. Azimi, S. Rabiee, and M. A. S. Rabiee, World J. Plast. Surg. 5, 39 (2016).
R. Burkhardt and N. P. Lang, Periodontol. 2000 68, 270 (2015).
L. Han, X. Lu, K. Liu, K. Wang, L. Fang, L.-T. Weng, H. Zhang, Y. Tang, F. Ren, C. Zhao, G. Sun, R. Liang, and Z. Li, ACS Nano 11, 2561 (2017).
H. Kim, W. H. Kong, K.-Y. Seong, D. K. Sung, H. Jeong, J. K. Kim, S. Y. Yang, and S. K. Hahn, Biomacromolecules 17, 3694 (2016).
X. Zhao, H. Wu, B. Guo, R. Dong, Y. Qiu, and P. X. Ma, Biomaterials 122, 34 (2017).
C. Bradford and B. J. Hamerslagh, Patent Application Publication (2018).
E. A. Kamoun, E.-R. S. Kenawy, and X. Chen, J. Adv. Res. 8, 217 (2017).
T. Gao, M. Jiang, X. Liu, G. You, W. Wang, Z. Sun, A. Ma, and J. Chen, Polymers 11, 171 (2019).
S. Ding, L. Feng, J. Wu, F. Zhu, Z. Tan, and R. Yao, ACS Biomater. Sci. Eng. 4, 3108 (2018).
N. Ojeh, I. Pastar, M. Tomic-Canic, and O. Stojadinovic, Int. J. Mol. Sci. 16, 25476 (2015).
D. E. Lee, N. Ayoub, and D. K. Agrawal, Stem Cell Res. Ther. 7, 37 (2016).
M. Tobita, S. Tajima, and H. Mizuno, Stem Cell Res. Ther. 6, 215 (2015).
J. Zhang, J. Guan, X. Niu, G. Hu, S. Guo, Q. Li, Z. Xie, C. Zhang, and Y. Wang, J. Transl. Med. 13, 49 (2015).
X. Liang, X. Huang, Y. Zhou, R. Jin, and Q. Li, Stem Cells Transl Med. 5, 960 (2016).
J. E. Millán-Rivero, C. M. Martínez, P. A. Romecín, S. D. Aznar-Cervantes, M. Carpes-Ruiz, J. L. Cenis, J. M. Moraleda, N. M. Atucha, and D. García-Bernal, Stem Cell Res. Ther. 10, 126 (2019).
How to Cite
APA
ACM
ACS
ABNT
Chicago
Harvard
IEEE
MLA
Turabian
Vancouver
Download Citation
CrossRef Cited-by
1. Ana Maria Chaves Cano, Alfredo Javier Pérez Gamboa, William Castillo-González . (2025). Regenerative medicine and tissue engineering from an innovative approach. eVitroKhem, 4, p.155. https://doi.org/10.56294/evk2025155.
2. João Guilherme Rodrigues Leandro, Alexandre Carneiro Silvino. (2024). POLICAPROLACTONA: POLIÉSTER COM POTENCIAL APLICAÇÃO NA CONFECÇÃO DE CURATIVOS. REVISTA FOCO, 17(11), p.e6741. https://doi.org/10.54751/revistafoco.v17n11-018.
Dimensions
PlumX
Article abstract page views
Downloads
License
Copyright (c) 2020 MOMENTO

This work is licensed under a Creative Commons Attribution-NoDerivatives 4.0 International License.
Those authors who have publications with this journal, accept the following terms:
a. The authors will retain their copyright and will guarantee the publication of the first publication of their work, which will be subject to the Attribution-SinDerivar 4.0 International Creative Commons Attribution License that permits redistribution, commercial or non-commercial, As long as the Work circulates intact and unchanged, where it indicates its author and its first publication in this magazine.
b. Authors are encouraged to disseminate their work through the Internet (eg in institutional telematic files or on their website) before and during the sending process, which can produce interesting exchanges and increase appointments of the published work.







