Review: Does Gabapentin Relieve Opioids, Cannabis and Methamphetamines Addictions?
Revisión: Alivia la Gabapentina las Adicciones a Opioides, Cannabis y Metanfetaminas?
Revisão: A Gabapentina Alivia Dependências de Opióide, Cannabis e Metanfetamina?
DOI:
https://doi.org/10.15446/.v29n1.75930Keywords:
Gabapentin, Cannabis, Methamphetamine, Opioids, Treatment (en)Gabapentina, Cannabis, Metanfetamina, Opioides, Tratamiento (es)
Gabapentina, Cannabis, Metanfetamina, Opioides, Tratamento (pt)
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The study reviews the suitability of using Gabapentin for treating opioid, cannabis and methamphetamine use disorders. This revision consists of 61 biographical references based on a PubMed database search (January of 1983-May of 2018). Gabapentin displayed respectively 50% and 66.7% of success for treating methamphetamine dependence and opioid withdrawal symptoms. Furthermore, a few research studies have reported Gabapentin´s efficacy for alleviating cannabis dependence (two studies), and cannabis withdrawal symptoms (one study). Similarly, a single study reported Gabapentin reduction of opioid consumption during the detoxification process. Based on the revision, we can conclude that: (a) Gabapentin is useful for treating opioid withdrawal symptoms, (b) additional studies are necessary for elucidating the effectiveness of Gabapentin for treating methamphetamine dependence, cannabis dependence and its withdrawal symptoms, and (c) more studies are necessary to confirm the efficacy of Gabapentin in reducing opioid consumption during detoxification.
El trabajo revisa 61 referencias bibliográficas, producto de una búsqueda en la base de datos PubMed (enero de 1983 a mayo de 2018), con el fin de determinar si la Gabapentina es adecuada para el tratamiento de trastornos derivados del uso de opiáceos, cannabis y metanfetaminas. El éxito de la Gabapentina para tratar la dependencia a las metanfetaminas y los síntomas de abstinencia de opiáceos fue de 50% y 66.7%, respectivamente. Algunas investigaciones han informado la eficacia de la Gabapentina para aliviar la dependencia al cannabis (dos estudios) y los síntomas de abstinencia del cannabis (un estudio). Un solo estudio reportó que la Gabapentina redujo el consumo de opiáceos, durante el proceso de desintoxicación. La revisión nos permite concluir que (a) la Gabapentina es útil para tratar los síntomas de abstinencia de los opiáceos, (b) se necesitan más estudios para esclarecer la efectividad de la Gabapentina para tratar la dependencia a las metanfetaminas, al cannabis y los síntomas de abstinencia, y (c) se requieren más estudios para confirmar la eficacia de la Gabapentina para reducir el consumo de opiáceos durante la desintoxicación.
O presente trabalho analisa a eficácia da gabapentina no tratamento de distúrbios de opiáceos, cannabis e metanfetaminas. Esta revisão consiste em 57 referências baseadas em pesquisa no repositório Pub Med (janeiro / 1983 - maio / 2018). A gabapentina mostrou respectivamente 50% e 66,7% de eficácia para tratar a dependência de metanfetaminas e a síndrome de abstinência de opióides. Além disso, há poucos relatos sobre a eficiência da gabapentina em aliviar a dependência (dois estudos) e a síndrome de abstinência (um estudo) à cannabis. Da mesma forma, um estudo relatou que a gabapentina reduz o consumo de opiáceos durante a desintoxicação. Esta avaliação conclui que: a) a gabapentina é útil para o tratamento da síndrome de abstinência de opióides, b) é necessário mais estudos para determinar se a gabapentina alivia dependência de dependência da metanfetamina e retirada de cannabis, e c) mais estudos são necessários para confirmar se a gabapentina reduz o consumo de opiáceos durante a desintoxicação.
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