Published

2021-05-01

Effect of phytobiotic - Germivit on the functional state of cattle

Efecto del fitobiótico - Germivit sobre el estado funcional del ganado

DOI:

https://doi.org/10.15446/rfnam.v74n2.85369

Keywords:

feed supplement, cattle, Germivit, metabolism, immunity (en)
Ganado, Suplemento alimenticio Germivit , Inmunidad , Metabolismo (es)

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Plant-based feed additives, also known as phytobiotics, show great promise to compensate deficiencies of important biologically active substances in the diet. Therefore, this study aimed to evaluate the effect of Germivit on the feed supplement of cattle of different ages. In the first experiment, four groups of 9-month-old Simmental calves (10 animals in each group) were fed with Germivit at 0.0, 0.5, 0.7, and 0.9 g kg-1 live body weight, respectively. In the second experiment, three groups of pregnant cows (10 animals in each group) received Germivit at 0.0, 0.25, and 0.50 kg-1 live body weight, respectively. The morphological composition of the collected blood was studied using a PCE-90vet automatic hematology analyzer. The blood biochemical composition was studied using a Stat Fax 1904 biochemical analyzer, and the immunological status of the animals was evaluated using generally accepted methods in veterinary medicine: immunocompetent cells by spontaneous rosette formation; immunoglobulins by the radial  immunodiffusion method; phagocytosis by using S. aureus culture; serum lysozyme activity by the photoelectrocolorimetric method; and bactericidal activity of serum by determining the degree of growth inhibition of the mixture of daily  culture of E. coli in a nutritive culture broth. Germivit contributed to the improvement of the biochemical and immunological parameters in the calves. In the cows, an increase in the morphological parameters of blood was observed, their immune status improved, and their calves were born with high rates of natural resistance and health. Germivit had a positive effect on the functional state of cattle.

Los aditivos de origen vegetal para alimento animal, también conocidos como fitobióticos, son muy prometedores para compensar una deficiencia de sustancias biológicamente activas importantes en la dieta. Este estudio tuvo como objetivo evaluar el efecto del Germivit como suplemento alimenticio del ganado de diferentes edades. En el primer experimento, cuatro grupos de terneros (10 animales en cada grupo) Simmental de 9 meses de edad fueron alimentados con Germivit a una dosis de 0,0; 0,5; 0,7 y 0,9 kg-1 de peso corporal vivo, respectivamente. En el segundo experimento, tres grupos de vacas preñadas (10 animales en cada grupo) recibieron Germivit a una dosis de 0,0; 0,25 y 0,50 g kg-1 de peso corporal vivo, respectivamente. La composición morfológica de la sangre recogida se estudió utilizando un analizador hematológico automático PCE-90vet. La composición bioquímica de la sangre se estudió utilizando un analizador bioquímico Stat Fax 1904, y el estado inmune de los animales se evaluó utilizando métodos generalmente aceptados en veterinaria: células inmunocompetentes por formación espontánea de rosetas; inmunoglobulinas por el método de inmunodifusión radial; fagocitosis usando cultivo de S. aureus; actividad de la lisozima sérica por el método fotoelectrocolorimétrico; y actividad bactericida del suero determinando el grado de inhibición del crecimiento de la mezcla de cultivo diario de E. coli en un medio nutritivo líquido. Germivit contribuyó a una mejora de los parámetros bioquímicos e inmunológicos en los terneros. En las vacas se observó un aumento de los parámetros morfológicos de la sangre, mejoró su estado inmunológico y sus terneros nacieron con altos índices de resistencia natural y salud. Germivit tuvo un efecto positivo sobre el estado funcional del ganado.

References

Ademola SG, Farinu GO, and Babatunde GM. 2009. Serum lipid, growth and haematological parameters of broilers fed garlic, ginger and their mixtures. World Journal of Agricultural Sciences 5(1): 99-104. http://www.idosi.org/wjas/wjas5(1)/15.pdf

Al-Yasiry ARM, Kiczorowska B, Samolińska W, KowalczukVasilev E, and Kowalczyk-Pecka D. 2017. The effect of Boswellia serrata resin diet supplementation on production, hematological, biochemical and immunological parameters in broiler chickens. Animal 11(11): 1890–1898. https://doi.org/10.1017/S1751731117000817

Borda-Molina D, Seifert J, and Camarinha-Silva A. 2018. Current perspectives of the chicken gastrointestinal tract and its microbiome. Computational and Structural Biotechnology Journal 16: 131–139. https://doi.org/10.1016/j.csbj.2018.03.002

Brogna DMR, Tansawat R, Cornforth D, Ward R, Bella M, Luciano G, and Villalba J. 2014. The quality of meat from sheep treated with tannin- and saponin-based remedies as a natural strategy for parasite control. Meat Science 96(2): 744–749. https://doi.org/10.1016/j.meatsci.2013.10.019

Castillo-López RI, Gutiérrez-Grijalva EP, Leyva-López N,López-Martínez LX and Heredia JB. 2017. Natural alternatives to growth-promoting antibiotics (GPA) in animal production. The Journal of Animal and Plant Sciences 27(2) 349–359. https://www.researchgate.net/publication/316671322_Natural_alternatives_to_growth-promoting_antibiotics_GPA_in_animal_production

Currò D, Ianiro G, Pecere S, Bibbò S and Cammarota G. 2017.Probiotics, fibre and herbal medicinal products for functional and inflammatory bowel disorders: Probiotics and nutraceuticals for IBS, CIC and IBD. British Journal of Pharmacology 174(11): 1426–1449. https://doi.org/10.1111/bph.13632

Donnik IM, Shkuratova IA, Rubinsky IA, Topuria GM, Chernokozhev AI and Topuria LY. 2010. Primeneniye germivita v zhivotnovodstve i veterinarii (the use of Germivit in livestock and veterinary medicine). Publishing Center VNIIMS, Orenburg. 96 p.

Drouillard JS. 2018. Current situation and future trends for beef production in the United States of America—A review. AsianAustralasian Journal of Animal Sciences 31(7): 1007–1016. https://doi.org/10.5713/ajas.18.0428

Franciosini MP, Casagrande-Proietti P, Forte C, Beghelli D, Acuti G, Zanichelli D, and Trabalza-Marinucci M. 2016. Effects of oregano (Origanum vulgare L.) and rosemary (Rosmarinus officinalis L.) aqueous extracts on broiler performance, immune function and intestinal microbial population. Journal of Applied Animal Research 44(1): 474–479. https://doi.org/10.1080/09712119.2015.1091322

Friedman M, Henika PR, and Mandrell RE. 2002. Bactericidal activities of plant essential oils and some of their isolated constituents against Campylobacter jejuni, Escherichia coli, Listeria monocytogenes, and Salmonella enterica. Journal of Food Protection 65(10): 1545–1560. https://doi.org/10.4315/0362-028X-65.10.1545

Hao H, Cheng G, Iqbal Z, Ai X, Hussain HI, Huang L, Dai M, Wang Y, Liu Z, and Yuan Z. 2014. Benefits and risks of antimicrobial use in food-producing animals. Frontiers in Microbiology 5: 288. https://doi.org/10.3389/fmicb.2014.00288

Karásková K, Suchý P, and Straková E. 2015. Current use of phytogenic feed additives in animal nutrition: a review. Czech Journal of Animal Science 60(12): 521–530. https://doi.org/10.17221/8594-CJAS

Kuhn G, Ender K, Thomann R, Tuchscherer M, Tuchscherer A, Stabenow B, Kruger M, and Schrodl W. 2005. Einsatz von Echinacea-extrakt bei tragenden und saugenden. Archives Animal Breeding 48: 270-282. https://doi.org/10.5194/AAB-48-270-2005

Kulmakova NI and Mudarisov RM. 2019. Immunobiologicheskiy status krupnogo rogatogo skota v sisteme «mat’-plodnovorozhdennyy» (Immunobiological status of cattle in the system ‘mother-fetus-newborn’). Megaprint, Irkutsk. 206 p.

Kulmakova NI, Mudarisov RM, and Khakimov IN. 2019. Produktivnyye kachestva krupnogo rogatogo skota i sokhrannost’ molodnyaka pri korrektsii immuniteta (Productive qualities of cattle and the safety of young animals with the correction of immunity). Izdatel’stvo Lan’, Saint-Petersburg. 156 p. https://lanbook.com/catalog/veterinariya/produktivnye-kachestva-krupnogo-rogatogoskota-i-sokhrannost-molodnyaka-pri-korrektsii-immuniteta

Kumar M, Kumar V, Roy D, Kushwaha R, and Vaswani S. 2014. Application of herbal feed additives in animal nutrition—A Review. International Journal of Livestock Research 4(9): 1-8. https://doi.org/10.5455/ijlr.20141205105218

Mohammadi Gheisar M and Kim IH. 2018. Phytobiotics in poultry and swine nutrition – a review. Italian Journal of Animal Science 17(1): 92–99. https://doi.org/10.1080/1828051X.2017.1350120

Mohiti-Asli M and Ghanaatparast-Rashti M. 2017. Comparison of the effect of two phytogenic compounds on growth performance and immune response of broilers. Journal of Applied Animal Research 45(1): 603–608. https://doi.org/10.1080/09712119.2016.1243119

Oguey C and Wall EH. 2016. A blend of cinnamaldehyde, eugenol, and capsicum oleoresin improves milking performance in lactating dairy cows. Journal of Animal Science 94(Suppl 5): 763– 763. https://doi.org/10.2527/jam2016-1570

Patel AP, Bhagwat SR, Pawar MM, Prajapati KB, Chauhan HD, and Makwana RB. 2016. Evaluation of Emblica officinalis fruit powder as a growth promoter in commercial broiler chickens. Veterinary World 9(2): 207–210. https://doi.org/10.14202/vetworld.2016.207-210

Pink-Lotus. 2020. Wheat Germ Flour. In: Pink Lotus, Russia. https://www.pink-lotus.ru/Manufacturer’s

Ramiah SK, Zulkifli I, Rahim NAA, Ebrahimi M, and Meng GY. 2014. Effects of two herbal extracts and Virginiamycin supplementation on growth performance, intestinal microflora population and fatty acid composition in broiler chickens. AsianAustralasian Journal of Animal Sciences 27(3): 375–382. https://doi.org/10.5713/ajas.2013.13030

Samii SS, Wallace N, Nagaraja TG, Engstrom MA, Miesner MD, Armendariz CK, and Titgemeyer EC. 2016. Effects of limonene on ruminal Fusobacterium necrophorum concentrations, fermentation, and lysine degradation in cattle. Journal of Animal Science 94(8): 3420–3430. https://doi.org/10.2527/jas.2016-0455

Shakhov AG. 2015. Rukovodstvo po otsenke i korrektsii immunnogo statusa zhivotnykh (Guidelines for the assessment and correction of the immune status of animals). Izdatel;stvo Istoki, Voronezh. 120 p.

Shawle K, Urge M, and Animut G. 2016. Effect of different levels of Lepidium sativum L. on growth performance, carcass characteristics, hematology and serum biochemical parameters of broilers. SpringerPlus 5(1): 1440-1441. https://doi.org/10.1186/s40064-016-3118-0

Stanley D, Hughes RJ, and Moore RJ. 2014. Microbiota of the chicken gastrointestinal tract: Influence on health, productivity and disease. Applied Microbiology and Biotechnology 98(10) 4301–4310. https://doi.org/10.1007/s00253-014-5646-2

Tosi G, Massi P, Antongiovanni M, Buccioni A, Minieri S, Marenchino L, and Mele M. 2013. Efficacy test of a hydrolysable tannin extract against necrotic enteritis in challenged broiler chickens. Italian Journal of Animal Science 12(3): 392-395. https://doi.org/10.4081/ijas.2013.e62

Trukhachev VI, Zlidnev NZ, and Samokish NV. 2015. Al’ternativa antibiotikam v ptitsevodstve (Alternative to antibiotics in poultry). Agricultural Bulletin of Stavropol Region 2(18): 149–153. http://www.vapk26.ru/journals.php

Valenzuela-Grijalva NV, Pinelli-Saavedra A, Muhlia-Almazan A, Domínguez-Díaz D, and González-Ríos H. 2017. Dietary inclusion effects of phytochemicals as growth promoters in animal production. Journal of Animal Science and Technology 59(1): 2-17. https://doi.org/10.1186/s40781-017-0133-9

Valero MV, Prado RM do, Zawadzki F, Eiras CE, Madrona GS, and Prado IN do. 2014. Propolis and essential oils additives in the diets improved animal performance and feed efficiency of bulls finished in feedlot. Acta Scientiarum. Animal Sciences 36(4): 419-426. https://doi.org/10.4025/actascianimsci.v36i4.23856

Wall EH and Bravo DM. 2016. 1554 Supplementation with rumen-protected capsicum oleoresin increases milk production and component yield in lactating dairy cows. Journal of Animal Science 94(Suppl. 5): 755. https://doi.org/10.2527/jam2016-1554

Windisch W, Schedle K, Plitzner C, and Kroismayr A. 2008. Use of phytogenic products as feed additives for swine and poultry. Journal of Animal Science 86 (Suppl. 14): E140–E148. https://doi.org/10.2527/jas.2007-0459

Yang Y, Iji PA, and Choct M. 2009. Dietary modulation of gut microflora in broiler chickens: a review of the role of six kinds of alternatives to in-feed antibiotics. World’s Poultry Science Journal 65(1): 97–114. https://doi.org/10.1017/S0043933909000087

How to Cite

APA

Topuria, L., Topuria, G. & Pirogov, V. (2021). Effect of phytobiotic - Germivit on the functional state of cattle. Revista Facultad Nacional de Agronomía Medellín, 74(2), 9549–9561. https://doi.org/10.15446/rfnam.v74n2.85369

ACM

[1]
Topuria, L., Topuria, G. and Pirogov, V. 2021. Effect of phytobiotic - Germivit on the functional state of cattle. Revista Facultad Nacional de Agronomía Medellín. 74, 2 (May 2021), 9549–9561. DOI:https://doi.org/10.15446/rfnam.v74n2.85369.

ACS

(1)
Topuria, L.; Topuria, G.; Pirogov, V. Effect of phytobiotic - Germivit on the functional state of cattle. Rev. Fac. Nac. Agron. Medellín 2021, 74, 9549-9561.

ABNT

TOPURIA, L.; TOPURIA, G.; PIROGOV, V. Effect of phytobiotic - Germivit on the functional state of cattle. Revista Facultad Nacional de Agronomía Medellín, [S. l.], v. 74, n. 2, p. 9549–9561, 2021. DOI: 10.15446/rfnam.v74n2.85369. Disponível em: https://revistas.unal.edu.co/index.php/refame/article/view/85369. Acesso em: 20 mar. 2026.

Chicago

Topuria, Larisa, Gocha Topuria, and Victor Pirogov. 2021. “Effect of phytobiotic - Germivit on the functional state of cattle”. Revista Facultad Nacional De Agronomía Medellín 74 (2):9549-61. https://doi.org/10.15446/rfnam.v74n2.85369.

Harvard

Topuria, L., Topuria, G. and Pirogov, V. (2021) “Effect of phytobiotic - Germivit on the functional state of cattle”, Revista Facultad Nacional de Agronomía Medellín, 74(2), pp. 9549–9561. doi: 10.15446/rfnam.v74n2.85369.

IEEE

[1]
L. Topuria, G. Topuria, and V. Pirogov, “Effect of phytobiotic - Germivit on the functional state of cattle”, Rev. Fac. Nac. Agron. Medellín, vol. 74, no. 2, pp. 9549–9561, May 2021.

MLA

Topuria, L., G. Topuria, and V. Pirogov. “Effect of phytobiotic - Germivit on the functional state of cattle”. Revista Facultad Nacional de Agronomía Medellín, vol. 74, no. 2, May 2021, pp. 9549-61, doi:10.15446/rfnam.v74n2.85369.

Turabian

Topuria, Larisa, Gocha Topuria, and Victor Pirogov. “Effect of phytobiotic - Germivit on the functional state of cattle”. Revista Facultad Nacional de Agronomía Medellín 74, no. 2 (May 1, 2021): 9549–9561. Accessed March 20, 2026. https://revistas.unal.edu.co/index.php/refame/article/view/85369.

Vancouver

1.
Topuria L, Topuria G, Pirogov V. Effect of phytobiotic - Germivit on the functional state of cattle. Rev. Fac. Nac. Agron. Medellín [Internet]. 2021 May 1 [cited 2026 Mar. 20];74(2):9549-61. Available from: https://revistas.unal.edu.co/index.php/refame/article/view/85369

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