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Interacciones hospedero-parásito
Keywords:
hospedero, parásito, Herpes simplex, Criptococcus, neofomums, Mycobacterium Leprae (es)Host, parasite, Herpes simplex, Criptococcus neoformans, Mycobacterium Leprae (en)
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La interacción hospedero-parásito juega un papel importante en la evolución de las enfermedades infecciosas. En este articulo se analiza esta interacción desde el punto de vista del hospedero, es decir de la respuesta inmune incluyendo los conceptos de la respuesta T1y T2 frente al microorganismo. En infecciones con lepra cada vez es más claro el papel de la respuesta T1/T2 y su relación con la evolución de la enfermedad, pero falta por esclarecer como un individuo responde con una u otra lo que se traduce en curación ó enfermedad. En las infecciones por Herpes simplex aunque no es tan claro el papel de la respuesta T1/T2 si lo es el de algunas citocinas tanto en la prirnoinfección, latencia y reactivación. Finalmente en las infecciones por Criptococcus neoformans, aunque las características propias del microorganismo se relacionan con la evolución de la infección, la respuesta inmune con perfil T1 se asocia con el control de la infección.
The interaction host-parasite plays an important role in the evolution of infectious diseases. This article seeks to analize this interaction from the point of view of the host, in relation to immune response including the concepts of T1 and T2 responses in front of the microorganismo T1 and T2 responses are clearer in infections like leprosy and its relation to the evolution of the diseases but it is n 't clear yet how an individual responds to one or the other which means cure or disease. ln Herpes simplex infections, although the role of the T1 and T2 responses is not so straight-forward so is the role of some cytokines in the primary infection, latency and reactivation. Finally, in Criptococcus neofonnans infections, the immune response with T1 profile is associated with the control of the infections, although the microorganism characteristics are related to the evolution of the infection.
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