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Aspectos bioquímicos y farmacológicos de la nialamida y su comparación con otros agentes inhibidores de la monomino-oxidasa (A. M. O.)
Keywords:
farmacología, bioquímica, nialamida (es)Downloads
En este trabajo se muestra la acción inhibidora sobre la monoaminoxidasa M. A. O. ocasionada por la yageína harmalina, la nialamida y la iproniacida, tanto in-vitro como invivo. Se ha valorado, en cerebro de ratón, el contenido de serotonina y de norepinefrina después de la administración de estas drogas y se midió la actividad de la M. A. O. Las aminas fueron estimadas fluorométricamente y los resultados obtenidos muestran niveles aumentados de serotonina y de norepinefrina en primer lugar, con yageína, en segundo lugar con nialamida y en tercer lugar con iproniacida.
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