Published

2018-03-01

Prescripción de paroxetina en adolescentes Colombianos

Prescription of paroxetine in Colombian adolescents

DOI:

https://doi.org/10.15446/rsap.v20n2.59067

Keywords:

Paroxetina, depresión, adolescente, farmacovigilancia (es)
Paroxetine, depression, adolescent, pharmacovigilance (en)

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Authors

  • Manuel Enrique Machado-Duque Universidad Tecnológica de Pereira - Audifarma S.A.
  • Claudia Giraldo-Giraldo Universidad Tecnológica de Pereira - Audifarma S.A.
  • Jorge Enrique Machado Alba Universidad Tecnológica de Pereira - Audifarma S.A.

Objetivo Determinar la frecuencia de uso de paroxetina en pacientes adolescentes menores de 20 años afiliados al sistema de salud colombiano.
Métodos Estudio de corte transversal, a partir de una base de datos poblacional de personas afiliadas al Sistema General de Seguridad Social en Colombia entre primero de enero 2011 y 31 diciembre 2015 buscando los pacientes menores de 20 años que hubiesen recibido cualquier presentación de paroxetina. Para el análisis de datos se establecieron frecuencias y proporciones.
Resultados Se hallaron 777 sujetos prescritos con paroxetina durante los cinco años de evaluación, con edad promedio de 53,8±16, dos años Solo 36 pacientes menores de 20 años lo recibían, especialmente hombres (n=24; 64,8%) con edad media de 17,7±1,8 años. La mayoría estaban siendo tratados en la ciudad de Bogotá (58,3%), seguidos de Medellín (16,7%) y Cartagena (8,3%).
Conclusiones Una baja proporción de adolescentes están recibiendo paroxetina en Colombia lo que reduce el riesgo que puede representar este fármaco para ellos.

Objective To determine the frequency of paroxetine use in adolescent patients under 20 years of age enrolled in the Colombian Health System.
Material and Methods Cross-sectional study, based on a population database of people enrolled in the Colombian Health System between January 1, 2011 and December 31, 2015. The sample included patients under 20 years of age who had received any presentation of paroxetine. For data analysis, frequencies and proportions were established.
Results 777 subjects were prescribed with paroxetine during the five years of evaluation, with an average age of 53.8 ± 16.2 years. Only 36 patients under 20 received it, especially men (n=24, 64.8%) with a mean age of 17.7 ± 1.8 years. Most of them were being treated in the city of Bogotá (58.3%), followed by Medellín (16.7%) and Cartagena (8.3%).
Conclusions A low proportion of adolescents are receiving paroxetine in Colombia, which reduces the risk that this drug may pose on them.

References

Kaufman J, Martin A, King RA, Charney D. Are child-, adolescent-, and adult-onset depression one and the same disorder? Biol Psychiatry. 2001;49 (12):980-1001.

Keller MB, Ryan ND, Strober M, Klein RG, Kutcher SP, Birmaher B, et al. Efficacy of paroxetine in the treatment of adolescent major depression: a randomized, controlled trial. J Am Acad Child Adolesc Psychiatry. 2001;40 (7):762-72.

Le Noury J, Nardo JM, Healy D, Jureidini J, Raven M, Tufanaru C, et al. Restoring Study 329: efficacy and harms of paroxetine and imipramine in treatment of major depression in adolescence. Bmj. 2015; 351:h4320.

Machado-Alba JE, Morales Plaza CD, Solarte Gomez MJ. [Antidepressant prescription patterns in patients affiliated with the General Social Security Health System of Colombia]. Rev Panam Salud Publica. 2011; 30(5):461-8.

Hetrick SE, McKenzie JE, Cox GR, Simmons MB, Merry SN. Newer generation antidepressants for depressive disorders in children and adolescents. Cochrane Database Syst Rev. 2012; 11:Cd004851.

How to Cite

APA

Machado-Duque, M. E., Giraldo-Giraldo, C. and Machado Alba, J. E. (2018). Prescripción de paroxetina en adolescentes Colombianos. Revista de Salud Pública, 20(2), 243–244. https://doi.org/10.15446/rsap.v20n2.59067

ACM

[1]
Machado-Duque, M.E., Giraldo-Giraldo, C. and Machado Alba, J.E. 2018. Prescripción de paroxetina en adolescentes Colombianos. Revista de Salud Pública. 20, 2 (Mar. 2018), 243–244. DOI:https://doi.org/10.15446/rsap.v20n2.59067.

ACS

(1)
Machado-Duque, M. E.; Giraldo-Giraldo, C.; Machado Alba, J. E. Prescripción de paroxetina en adolescentes Colombianos. Rev. salud pública 2018, 20, 243-244.

ABNT

MACHADO-DUQUE, M. E.; GIRALDO-GIRALDO, C.; MACHADO ALBA, J. E. Prescripción de paroxetina en adolescentes Colombianos. Revista de Salud Pública, [S. l.], v. 20, n. 2, p. 243–244, 2018. DOI: 10.15446/rsap.v20n2.59067. Disponível em: https://revistas.unal.edu.co/index.php/revsaludpublica/article/view/59067. Acesso em: 22 jan. 2025.

Chicago

Machado-Duque, Manuel Enrique, Claudia Giraldo-Giraldo, and Jorge Enrique Machado Alba. 2018. “Prescripción de paroxetina en adolescentes Colombianos”. Revista De Salud Pública 20 (2):243-44. https://doi.org/10.15446/rsap.v20n2.59067.

Harvard

Machado-Duque, M. E., Giraldo-Giraldo, C. and Machado Alba, J. E. (2018) “Prescripción de paroxetina en adolescentes Colombianos”, Revista de Salud Pública, 20(2), pp. 243–244. doi: 10.15446/rsap.v20n2.59067.

IEEE

[1]
M. E. Machado-Duque, C. Giraldo-Giraldo, and J. E. Machado Alba, “Prescripción de paroxetina en adolescentes Colombianos”, Rev. salud pública, vol. 20, no. 2, pp. 243–244, Mar. 2018.

MLA

Machado-Duque, M. E., C. Giraldo-Giraldo, and J. E. Machado Alba. “Prescripción de paroxetina en adolescentes Colombianos”. Revista de Salud Pública, vol. 20, no. 2, Mar. 2018, pp. 243-4, doi:10.15446/rsap.v20n2.59067.

Turabian

Machado-Duque, Manuel Enrique, Claudia Giraldo-Giraldo, and Jorge Enrique Machado Alba. “Prescripción de paroxetina en adolescentes Colombianos”. Revista de Salud Pública 20, no. 2 (March 1, 2018): 243–244. Accessed January 22, 2025. https://revistas.unal.edu.co/index.php/revsaludpublica/article/view/59067.

Vancouver

1.
Machado-Duque ME, Giraldo-Giraldo C, Machado Alba JE. Prescripción de paroxetina en adolescentes Colombianos. Rev. salud pública [Internet]. 2018 Mar. 1 [cited 2025 Jan. 22];20(2):243-4. Available from: https://revistas.unal.edu.co/index.php/revsaludpublica/article/view/59067

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CrossRef citations1

1. Juan‐Sebastian Franco, David Vizcaya. (2020). Availability of secondary healthcare data for conducting pharmacoepidemiology studies in Colombia: A systematic review. Pharmacology Research & Perspectives, 8(5) https://doi.org/10.1002/prp2.661.

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