Published

2000-07-01

TAMAÑO DE LA MUESTRA EN ANÁLISIS DE SOBREVIDA

Keywords:

Error tipo I, potencia, tasa de riesgo, censura, seguimiento (es)
Type I error, Power, Hazard function, Censoring, Follow-up (en)

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Authors

  • Javier Castañeda Pontificia Universidad Javeriana
  • Adriana Pérez Pontificia Universidad Javeriana
  • Jacky Gil Pontificia Universidad Javeriana
Este artículo presenta algunas expresiones y tablas de fácil manejo para la determinación del tamaño de la muestra necesario en la estimación de una tasa de riesgo específica y para comparar las tasas de riesgo entre dos grupos para varios escenarios de censura y seguimiento en un análisis de sobrevida. Se discuten algunas ventajas y desventajas en el empleo de las fórmulas presentadas.
This article presents some formulae and tables of easy use to handle the minimum sample size requirements in survival analysis. Sample size formulae are presented to estimate a specific hazard ratio, to compare two hazard ratios under several scenarios of censoring and follow up as well as to test the proportional hazard ratio assumption. A discussion about the advantages and disadvantages on the use of the presented formulae is presented.

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Copyright (c) 2000 Revista Colombiana de Estadística

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