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RADIOPHARMACEUTICAL RENAL DOSIMETRY USING SNYDER / CRISTY-ECKERMAN / SEGARS ANTHROPOMORPHIC REPRESENTATIONS
DOSIMETRÍA RENAL DE RADIOFÁRMACOS UTILIZANDO REPRESENTACIONES ANTROPOMÓRFICAS DE SNYDER / CRISTY-ECKERMAN / SEGARS
DOI:
https://doi.org/10.15446/mo.n68.102552Keywords:
MIRD dosimetry, Snyder/Cristy-Eckerman /Segars representations for kidneys (en)Dosimetría MIRD, representaciones de riñones Cristy-Eckerman/Segars (es)
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Absorbed doses to the kidneys of adult patients are estimated using the Medical Internal Radiation Dosimetry (MIRD) methodology and the anthropomorphic representations of Snyder, Cristy-Eckerman, and Segars. The radiopharmaceuticals 99mTc(DTPA), 99mTc(DMSA) and 99mTc(MAG3) are used to perform renal function studies in adults. The dose results found for these radiopharmaceuticals and their representations will allow the exploring of their dosimetric impact on each other. The relative difference in total renal dose by using the Snyder/Segars and Cristy-Eckerman/Segars anthropomorphic-representations was 3.6% and 0.3% when using 99mTc(DMSA); 2.9% and 3.0% when using 99mTc(MAG3); 5.0% and 1.5% when using 99mTc(DTPA). Regardless of the radiopharmaceutical selected, the substitution of Segars phantoms for Snyder or Cristy-Eckerman phantoms does not reflect significant changes in the estimated absorbed dose to the kidneys.
Se estiman las dosis absorbidas por los riñones de pacientes adultos utilizando la metodología Medical Internal Radiation Dosimetry (MIRD) y las representaciones antropomórficas de Snyder, Cristy-Eckerman, y de Segars. Los radiofármacos 99mTc (DTPA), 99mTc (DMSA) y 99mTc (MAG3) se utilizan para realizar estudios de función renal en adultos. Los resultados de dosis encontrados para estos radiofármacos y sus representaciones permitirán explorar su impacto dosimétrico entre ellas. La diferencia relativa en la dosis renal total al utilizar las representaciones antropomórficas de Snyder/Segars y Cristy-Eckerman/Segars fue del 3,6 % y del 0,3 % al utilizar 99mTc (DMSA); 2,9% y 3,0% cuando se usa 99mTc(MAG3); 5,0% y 1,5% cuando se utiliza 99mTc(DTPA). Independientemente del radiofármaco seleccionado, la sustitución de los fantomas de Segars por los fantomas de Snyder o Cristy-Eckerman no refleja cambios significativos en la dosis absorbida estimada en los riñones.
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