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NON-CONVENTIONAL PET NUCLIDES: PRODUCTION AND IMAGING
NUCLEIDOS DE PET NO CONVENCIONALES: PRODUCCIÓN Y PROYECCIÓN DE IMÁGEN
Keywords:
Cyclotrons, PET Radionuclides, cascade gamma, positron range. (en)Radionúcleos de PET, cascada de rayos gama, ciclotrón, rango de positrones. (es)
Medical cyclotrons are now commonly used for the production of PET nuclides by the (pn) reaction. These devices are typically capable of delivering 10-15 MeV protons beams at sufficiently high intensity for timely production of β+ decaying nuclides. Non-conventional PET nuclides have emerged recently and offers new opportunities for diagnostic and therapy drug discovery. In this paper, we will review the production capabilities for such nuclides at Washington University Medical School in St. Louis and present their production. Finally, challenges for imaging imposed by the specific of the decay characteristics will be discussed.
Los ciclotrones médicos son usados actualmente para la producción de Nucleidos de PET. Esos dispositivos son capaces de producir haces de protones de 10-15 MeV con suficiente intensidad para la producción de radionúcleos con decaimiento β+. Los nucleidos no convencionales de PET han surgido recientemente y ofrecen nuevas oportunidades para diagnóstico y farmacoterapia. En este artículo se hará mención de la capacidad de producción de tales nucleidos en la Washington University Medical School. Serán discutidos los retos en imagenología impuestos por las características del decaimiento.
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