Publicado

2014-01-01

Solubility of phenytoin in aqueous mixtures of ethanol and sodium dodecyl sulfate at 298 K

Solubilidad de la fenitoína en mezclas acuosas de etanol y dodecil-sulfato sódico a 298 K

Palabras clave:

solubility, phenytoin, ethanol, solvent mixture, sodium dodecyl sulfate, Jouyban-Acree model. (en)
solubilidad, fenitoína, etanol, mezcla solvente, dodecil-sulfato sódico, modelo de Jouyban-Acree. (es)

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Autores/as

  • Abolghasem Jouyban Tabriz University of Medical Sciences
  • Vahid Panahi-Azar Tabriz University of Medical Sciences
  • Mohammad A. A. Fakhree Tabriz University of Medical Sciences
  • Somaieh Ahmadian Tabriz University of Medical Sciences
The solubility of phenytoin in binary mixtures of ethanol + water at 298.2 K in the presence of three different concentrations of sodium dodecyl sulfate (sds) was reported. The Jouyban-Acree model was used for correlating the generated data and the obtained mean relative deviation was 7.3%. When all data points of phenytoin in binary solvents at various sds concentrations were fitted to the model, the obtained mean relative deviation was 10.1%.

Se presenta la solubilidad de la fenitoína a 298,2 K en mezclas binarias de etanol y agua en presencia de tres diferentes concentraciones de dodecil-sulfato sódico (dss). Se utiliza el modelo de Jouyban-Acree para correlacionar los datos generados obteniendo una desviación media relativa de 7,3%. Al ajustar al modelo todos los datos obtenidos de la fenitoína en los solventes binarios y en las diferentes concentraciones de dss la desviación media relativa obtenida fue de 10,1%.

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Citas

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Derechos de autor 2014 Revista Colombiana de Ciencias Químico-Farmacéuticas

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