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Synthesis and physicochemical studies of vanillin chalcones
Síntesis y estudios fisicoquímicos de vainillin-chalconas
DOI:
https://doi.org/10.15446/rcciquifa.v47n2.73966Palabras clave:
Synthesis, Chalcones, NN dimethyl formamide, chloroform, acoustical properties, refractive index, conductance, partition coefficient (en)Síntesis, chalconas, NN-dimetil formamida, cloroformo, propiedades acústicas, índice de refracción, conductancia, coeficiente de reparto (es)
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Some chalcone compounds are synthesized and their characterization was done by spectroscopic techniques such as IR, NMR and mass spectrometry. Some physicochemical properties such as acoustical properties, refractive index, conductance and partition coefficient have been studied for these synthesized compounds in N, N-dimethyl formamide and chloroform at 303.15 K. The studied properties are useful in QSAR studies and applications of these compounds in various other fields. It is observed that these parameters are affected by solvent and substitutions present in compounds.
Se sintetizaron algunos compuestos del tipo chalcona y su caracterizaron mediante técnicas espectroscópicas tales como IR, RMN y espectrometría de masa. Algunas propiedades fisicoquímicas tales como propiedades acústicas, índice de refracción, conductancia y coeficiente de reparto se estudiaron, para los compuestos sintetizados, en N,N-dimetil formamida y cloroformo a 303,15 K. Las propiedades estudiadas son útiles en estudios QSAR y en aplicaciones de estos compuestos en otros campos. Se observa que estos parámetros se ven afectados por el disolvente y las sustituciones presentes en los compuestos.
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1. Sema Akay, Berkant Kayan, Abolghasem Jouyban, Fleming Martínez, William E. Acree. (2021). Equilibrium solubility of vanillin in some (ethanol + water) mixtures: determination, correlation, thermodynamics and preferential solvation. Journal of Molecular Liquids, 342, p.117529. https://doi.org/10.1016/j.molliq.2021.117529.
2. Pintu Pathare, Sunil Tekale, Rafique Shaikh, Manoj Damale, Jaiprakash Sangshetti, Dhanaji Rajani, Rajendra Pawar. (2020). Pyridine and Benzoisothiazole Decorated Vanillin Chalcones: Synthesis, Antimicrobial, Antioxidant, Molecular Docking Study and ADMET Properties. Current Organic Synthesis, 17(5), p.367. https://doi.org/10.2174/1570179417666200407130122.
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