Published

2024-01-22

Perfil químico e atividades farmacológicas da Punica granatum (Punicaceae): uma revisão

Chemical profile and pharmacological activities of Punica granatum (Punicaceae): a review

Perfil químico y actividades farmacológicas de Punica granatum (Punicaceae): una revisión

DOI:

https://doi.org/10.15446/rcciquifa.v52n2.107461

Keywords:

Romã, Farmacologia, Fitoquímica (pt)
Pomegranate, pharmacology, phytochemistry (en)
Granada, farmacología, fitoquímica (es)

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Introdução: a Punica granatum é objeto de estudo de múltiplos pesquisadores, pois a espécie possui compostos químicos nas folhas, raízes, cascas, suco e caule, sendo uma fonte de taninos, saponinas, polifenóis, flavonoides entre muitas outras substâncias. Objetivo: descrever o perfil fitoquímico e as atividades farmacológicas da Punica granatum. Metodologia: o estudo trata-se de uma revisão bibliográfica com foco em artigos publicados na última década (2013-2012), utilizando as bases de dados Scopus, Embase, Web of Science e PubMed-Medline como fontes primárias de pesquisa e utilizando o software gratuito Ryyan para análise dos estudos relevantes que integram a revisão final. Resultados: os estudos incluídos descrevem a romã como uma espécie rica em compostos químicos, como flavonoides, ácidos orgânicos e polifenóis. Enquanto as atividades farmacológicas, incluem atividade anti-helmíntica, antidiabética, anti-inflamatória, antimicrobiana, anticarcinogênica e ações frente a prevenção e tratamento da doença de Alzheimer. Conclusão: a diversidade de compostos pode representar uma fonte viável para produção de fármacos e cosméticos com atividades de funções biológicas relevantes a saúde humana.

Introduction: Punica granatum is the object of study by multiple researchers because the species has chemical compounds in leaves, roots, barks, juice, and stem, being a source of tannins, saponins, polyphenols, flavonoids among many other substances. Aim: To describe the phytochemical profile and pharmacological activities of Punica granatum. Methodology: The study is a bibliographic review focusing on articles published in the last decade (2013-2012), using the Scopus, Embase, Web of Science and PubMed-Medline databases as primary sources of research and using the free Ryyan software for analysis of the relevant studies that integrate the final review. Results: The included studies describe pomegranate as a species rich in chemical compounds such as flavonoids, organic acids, and polyphenols. While pharmacological activities include anthelmintic, antidiabetic, anti-inflammatory, antimicrobial, anticarcinogenic activity and actions against the prevention and treatment of Alzheimer’s disease. Conclusion: The diversity of compounds may represent a viable source to produce drugs and cosmetics with activities of biological functions relevant to human health.

Introducción: Punica granatum es objeto de estudio por múltiples investigadores, pues la especie posee compuestos químicos en hojas, raíces, cortezas, jugo y tallo, siendo fuente de taninos, saponinas, polifenoles, flavonoides entre muchas otras sustancias. Objetivo: describir el perfil fitoquímico y las actividades farmacológicas de Punica granatum. Metodología: el estudio es una revisión bibliográfica centrada en artículos publicados en la última década (2013-2012), utilizando las bases de datos Scopus, Embase, Web of Science y PubMed-Medline como fuentes primarias de investigación y utilizando el software gratuito Ryyan para el análisis de los estudios relevantes que integran la revisión final. Resultados: los estudios incluidos describen la granada como una especie rica en compuestos químicos como flavonoides, ácidos orgánicos y polifenoles. Mientras que las actividades farmacológicas incluyen actividades antihelmínticas, antidiabética, antiinflamatoria, antimicrobiana, anticancerígena y acciones contra la prevención y el tratamiento de la enfermedad de Alzheimer. Conclusión: la diversidad de compuestos puede representar una fuente viable para la producción de medicamentos y cosméticos con actividades de funciones biológicas relevantes para la salud humana.

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APA

da Silva Pereira Rodrigues, A. R. and Carvalho de Alencar, C. D. (2024). Perfil químico e atividades farmacológicas da Punica granatum (Punicaceae): uma revisão. Revista Colombiana de Ciencias Químico-Farmacéuticas, 52(2). https://doi.org/10.15446/rcciquifa.v52n2.107461

ACM

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da Silva Pereira Rodrigues, A.R. and Carvalho de Alencar, C.D. 2024. Perfil químico e atividades farmacológicas da Punica granatum (Punicaceae): uma revisão. Revista Colombiana de Ciencias Químico-Farmacéuticas. 52, 2 (Jan. 2024). DOI:https://doi.org/10.15446/rcciquifa.v52n2.107461.

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da Silva Pereira Rodrigues, A. R.; Carvalho de Alencar, C. D. Perfil químico e atividades farmacológicas da Punica granatum (Punicaceae): uma revisão. Rev. Colomb. Cienc. Quím. Farm. 2024, 52.

ABNT

DA SILVA PEREIRA RODRIGUES, A. R.; CARVALHO DE ALENCAR, C. D. Perfil químico e atividades farmacológicas da Punica granatum (Punicaceae): uma revisão. Revista Colombiana de Ciencias Químico-Farmacéuticas, [S. l.], v. 52, n. 2, 2024. DOI: 10.15446/rcciquifa.v52n2.107461. Disponível em: https://revistas.unal.edu.co/index.php/rccquifa/article/view/107461. Acesso em: 12 jul. 2024.

Chicago

da Silva Pereira Rodrigues, Antonio Rony, and Cicero Damon Carvalho de Alencar. 2024. “Perfil químico e atividades farmacológicas da Punica granatum (Punicaceae): uma revisão”. Revista Colombiana De Ciencias Químico-Farmacéuticas 52 (2). https://doi.org/10.15446/rcciquifa.v52n2.107461.

Harvard

da Silva Pereira Rodrigues, A. R. and Carvalho de Alencar, C. D. (2024) “Perfil químico e atividades farmacológicas da Punica granatum (Punicaceae): uma revisão”, Revista Colombiana de Ciencias Químico-Farmacéuticas, 52(2). doi: 10.15446/rcciquifa.v52n2.107461.

IEEE

[1]
A. R. da Silva Pereira Rodrigues and C. D. Carvalho de Alencar, “Perfil químico e atividades farmacológicas da Punica granatum (Punicaceae): uma revisão”, Rev. Colomb. Cienc. Quím. Farm., vol. 52, no. 2, Jan. 2024.

MLA

da Silva Pereira Rodrigues, A. R., and C. D. Carvalho de Alencar. “Perfil químico e atividades farmacológicas da Punica granatum (Punicaceae): uma revisão”. Revista Colombiana de Ciencias Químico-Farmacéuticas, vol. 52, no. 2, Jan. 2024, doi:10.15446/rcciquifa.v52n2.107461.

Turabian

da Silva Pereira Rodrigues, Antonio Rony, and Cicero Damon Carvalho de Alencar. “Perfil químico e atividades farmacológicas da Punica granatum (Punicaceae): uma revisão”. Revista Colombiana de Ciencias Químico-Farmacéuticas 52, no. 2 (January 22, 2024). Accessed July 12, 2024. https://revistas.unal.edu.co/index.php/rccquifa/article/view/107461.

Vancouver

1.
da Silva Pereira Rodrigues AR, Carvalho de Alencar CD. Perfil químico e atividades farmacológicas da Punica granatum (Punicaceae): uma revisão. Rev. Colomb. Cienc. Quím. Farm. [Internet]. 2024 Jan. 22 [cited 2024 Jul. 12];52(2). Available from: https://revistas.unal.edu.co/index.php/rccquifa/article/view/107461

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