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Evaluación del monitoreo de anticonvulsivantes en un centro de referencia para el tratamiento de la epilepsia en Bogotá
Therapeutic monitoring evaluation of antiepileptic drugs in a reference center for the treatment of the epilepsy in Bogotá
Keywords:
Monitoreo de fármacos – Anticonvulsivantes - Farmacocinética clínica en Colombia. (es)Therapeutic drug monitoring -Antiepileptic drugs - Clinical Pharmacokinetic in Colombia. (en)
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In order to evaluate the anticonvulsant monitoring in a Colombian reference center, an observational, descriptive, and retrospective study was made analyzing 1017 consultations of 272 patients who entered by the first time in the institution during August 1998 to August 2000. The Guidelines for Therapeutic Monitoring on Antiepileptic Drugs elaborated by the Commission on Antiepileptic Drugs of the International League against Epilepsy were the parameters used for comparison. The blood levels were prescribed in 32.1%, of the consultations that need them. The patients’ compliance was 11.2%. The blood level reports do not have information about the therapeutic regimen, timing of the last dosage, and timing of the blood sample. In the reference center there is not have an appropriate compliance of the therapeutic drug monitoring. The information obtained is not enough and the pharmacokinetic estimates can not be made. It is noted the absence of Pharmacist staff in this process.
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Copyright (c) 2003 Revista Colombiana de Ciencias Químico-Farmacéuticas
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