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A descrição matemática da detecção eletroquímica da ergina, assistida pelos novos derivados triazólicos, dopados pelo íon amavadina
The mathematical description for the ergin electrochemical detection, assisted by amavadin ion doped triazolic derivatives
Descripción matemática de la detección electroquímica de ergina, asistida por los nuevos derivados de triazol, dopados por el ión amavadina
DOI:
https://doi.org/10.15446/rcciquifa.v50n1.95451Keywords:
Ergina, sensor eletroquímico, triazóis, amavadina, polímeros condutores, estado estacionário estável (pt)Ergina, sensor electroquímico, triazoles, amavadina, polímeros conductores, estado estacionario estable (es)
Ergin, electrochemical sensor, triazoles, amavadin, conducting polymers, stable steady-state (en)
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Introdução: pela primeira vez, o processo eletroanalítico da detecção da ergina (LSA) sobre um elétrodo, modificado por um derivado triazólico, dopado pelo íon amavadina, tem sido descrito teoricamente. Métodos: o modelo matemático, correspondente ao desempenho do sensor, tem sido desenvolvido e analisado do ponto de vista da teoria de estabilidade linear. Foi mostrado que a amavadina pode servir de modificador eficiente para a detecção eletroanalítica da ergina. Outrossim, a presença de um material orgânico no modificador reforça a capacidade da ergina de polimerizar-se, formando um compósito polimérico. Resultados: os comportamentos oscilatório e monotônico são mais prováveis que no caso mais comum, haja vista a formação-deformação de compostos iônicos aquando da detecção eletroanalítica.
Introduction: For the first time, the electroanalytical process of ergin (LSA) determination over an electrode, modified by triazolic derivative, doped by an amavadin-ion, has been theoretically described. Methods: The mathematical model, correspondent to the sensor function, has been developed and analyzed by means of linear stability theory. It has been shown that the amavadin may serve as an efficient electrode modifier for the electroanalytical detection of ergin. Moreover, the presence of an organic material as electrode modifier reinforces the possibility of ergin polymerization, yielding a polymer composite. Results: The oscillatory and monotonic behavior is more probable than in the common case, considering the formation and destruction of the ionic compounds during the electroanalytical detection.
Introducción: por primera vez se ha descrito teóricamente el proceso eletroanalítico de detección de ergina (LSA) en un electrodo, modificado por un derivado triazólico, dopado por el ión amavadina. Métodos: el modelo matemático, correspondiente al rendimiento del sensor, ha sido desarrollado y analizado desde el punto de vista de la teoría de la estabilidad lineal. Se ha demostrado que la amavadina puede servir como un modificador eficaz para la detección eletroanalítica de ergina. Además, la presencia de un material orgánico en el modificador refuerza la capacidad de la ergina para polimerizar, formando un compuesto polimérico. Resultados: los comportamientos oscilatorios y monótonos son más probables que en el caso más común, dada la formación-deformación de compuestos iónicos durante la detección eletroanalítica.
References
C. Ponté, M. Lapeyre-Mestre, Psychoactive effects of ‘legal high’: About lysergic acid amide (LSA), Therapie, 72, 605-608 (2017).
S. Legriel, F. Bruneel, O. Spreux-Varoguaux et al., Lysergic acid amide-induced posterior reversible encephalopathy syndrome with status epilepticus, Neurocrit. Care, 9, ID 247 (2008).
M. Meira, E. Pereira da Silva, J. P. David, J. P. David, Review of the genus Ipomoea: traditional uses, chemistry and biological activities, Rev. Bras. Farmacogn., 22, 682-713 (2012).
N. Kaur, W. Cooper, J. M. Duringer et al., Survival and development of potato psyllid (Hemiptera: Triozidae) on Convolvulaceae: Effects of a plant-fungus symbiosis (Periglandula), PLoS One, 13, e0201506 (2018).
M. Chary, D. Li, A. Manini, Candyflipping and other combinations: Identifying drug–drug combinations from an online forum, Front Psychiatry, 9, 135 (2018).
I. Mercurio, P. Melai, D. Capano et al., GC/MS analysis of morning glory seeds freely in commerce: can they be considered “herbal highs”? Egypt J. For. Sci., 7, ID 16 (2017).
A. Moubarak, E. Piper, Z. Johnson, M. Flieger, HPLC Method for detection of ergotamine, ergosine, and ergine after intravenous injection of a single dose, J. Agric. Food Chem., 44, 146-148 (1996).
J. Nowak, L. Wozniakiewicz, P. Klepacki et al., Identification and determination of ergot alkaloids in Morning Glory cultivars, Anal. Bioanal. Chem., 408, 3093- 3102 (2016).
R. Eker, S. Yilmaz, S. Yagmur, O. Yavintas, Voltammetric determination of clozapine from its drug form, J. Sci. Persp., 1, 19-30 (2017).
H. Aleixo, L. Okumura, A. Silva et al., Adsorptive stripping voltammetric determination of oxolinic acid in water sample, J. Braz. Chem. Soc., 29, 1417-1430 (2018).
J. da Silva, J.R.F. da Silva, A. Pombeiro, Amavadin, a vanadium natural complex: Its role and applications, Coordin. Chem. Rev., 257, 2388-2400 (2013).
M.T. Domarus, Studies of Amavadin and Related Complexes, M.Sc. Thesis, Universidade do Lisboa, 2014.
I.I. Aksyonova, O.I. Panasenko, Ye. G. Knysh, Synthesis and physical-chemical properties of 3-(4-(tert-butyl)phenyl)-5-(R-ylthio)-4H-1,2,4-triazol-4-amines, Act. Probl. Med. Pharm. Sci., 20, 31-34 (2016).
V.M. Odyntsova, Ye. S. Pruglo, A.S. Gotsulya et al., Antihypoxic activity of salts of (2-(5-(adamantane-1-yl)-4H-1,2,4-triazole-3-ylthio) acetate acids, Zapor. J. Med., 2, 94-96 (2014).
D. Sazou, The dynamic behavior of the electrochemical polymerization of indole in acetonitrile - water mixtures, Synth. Metals, 130, 45-55 (2002).
I. Das, N. Goel, N.R. Agrawal, S.K. Gupta, Growth patterns of dendrimers and electric potential oscillations during electropolymerization of pyrrole using mono- and mixed surfactants, J. Phys. Chem., 114, 12888-12893 (2010).
M. Bazzaoui, E.A. Bazzaoui, L. Martins, J.I. Martins, Electropolymerization of pyrrole on zinc-lead-silver alloys’ electrodes in neutral and acid organic media, Synth. Metals, 130, 73-80 (2002).
V. Tkach, B. Kumara-Swamy, R. Ojani et al., El mecanismo de la oxidación de omeprazol sobre el electrodo de carbono vitroso, modificado por polializarina y su descripción matemática, Orbital Elec. J. Chem., 7, 1-5 (2017).
P. Manisankar, G. Selvanathan, C. Vedhi, Utilisation of polypyrrole modified electrode for the determination of pesticide, Int. J. Env. Anal. Chem., 85, 409-422 (2005).
V.V. Tkach, M.V. Kushnir, S.C. de Oliveira et al., Electrochemical determination of Sudan dyes and two manner to realize it: a theoretical investigation, Lett. Appl. NanoBioSci., 9, 1451-1458 (2020).
V.V. Tkach, M.V. Kushnir, S.C. de Oliveira et al., The theoretical description for the electrochemical determination of anti-COVID-19 drug umifenovir, assisted by a poly(squaraine dye-co-naphthoquinones) composite with CoO(OH), paired with CoO2, Lett. Appl. NanoBioSci., 10, 1962-1968 (2021).
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