Repercusiones endocrinológicas del síndrome de apnea-hipopnea obstructiva del sueño (SAHOS)

Volumen 64,Numero 1, Suplemento SAHOS, Revista de la Facultad de Medicina

Publicado

2017-08-02

Repercusiones endocrinológicas del síndrome de apnea-hipopnea obstructiva del sueño (SAHOS)

Endocrinological implications of the obstructive sleep apnea-hypopnea syndrome (OSAHS)

Palabras clave:

Síndromes de la apnea del sueño, Obesidad, Diabetes mellitus, Osteoporosis. (es)
Sleep Apnea Syndromes, Obesity, Diabetes Mellitus, Osteoporosis. (en)

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Autores/as

Natalia Londoño-Palacio Clínica del Country - Bogotá D.C. - Colombia.
Álvaro Fernando Rico-López Fundación para la Investigación en Diabetes y Endocrinología - Sogamoso - Colombia

Resumen (es)
Resumen (en)

El síndrome de apnea-hipopnea obstructiva del sueño (SAHOS), como enfermedad multisistémica, afecta también el sistema endocrinológico: la producción normal de las hormonas se puede afectar ante la presencia de hipoxia intermitente, inflamación y estrés oxidativo. Por ejemplo, los sujetos con obesidad y SAHOS tienen niveles de leptina mucho más elevados que sujetos obesos pareados sin SAHOS. En el presente artículo se trata la relación existente entre la apnea del sueño y la obesidad, el síndrome metabólico (SM), la diabetes mellitus tipo 2 (DM2), los desórdenes neuroendocrinos y la osteoporosis.

Since obstructive sleep apnea-hypopnea syndrome (OSAHS) is a multisystemic disease, it also affects the endocrine system. Normal production of hormones can be influenced by the presence of intermittent hypoxia, inflammation, and oxidative stress; for example, subjects with obesity and OSAHS have much higher leptin levels than obese subjects without OSAHS. This article discusses the relationship between sleep apnea and obesity, metabolic syndrome (MS), diabetes mellitus type 2 (DM2), neuroendocrine disorders and osteoporosis.

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Citas

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