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Evaluación del uso de la radiación UV y ozono en la degradación de algunas sulfonamidas
Evaluation of the use of UV radiation and ozone in the degradation of some sulfonamides
Avaliação do uso da radiação UV e do ozônio na degradação de algumas sulfonamidas
DOI:
https://doi.org/10.15446/rcciquifa.v52n3.112482Palabras clave:
contaminantes emergentes, fármacos, tratamiento de aguas, ozonización, radiación UV (es)emerging contaminants, drugs, water treatment, ozonation, UV radiation (en)
contaminantes emergentes, drogas, tratamento de água, ozonização, radiação UV (pt)
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Introducción: los antibióticos en el medio acuático son un problema importante debido a la aparición de resistencia bacteriana. Se desconoce el impacto ecológico a largo plazo en el medio ambiente acuático. Muchas fuentes permiten la entrada de antibióticos al medio ambiente, incluidas las plantas de tratamiento de aguas residuales (PTAR), la escorrentía agrícola, los efluentes hospitalarios y los lixiviados de vertederos. Objetivo: se presenta un estudio que evalúa la degradación de la sulfadiazina (SD), sulfamerazina (SMR) y sulfametazina (SMT) al ser expuesta a condiciones de estrés por radiación UV, ozonificación y UV + ozonificación. Metodología: todos los análisis se realizaron mediante espectrofotometría UV/Vis luego de verificar mediante análisis de HPLC que los productos de degradación no interferían de manera significativa la absorbancia de los fármacos en estudio. Resultados: se demostró que las tres sulfonamidas son sensibles a todos los métodos de degradación estudiados, siendo el método más eficiente la combinación de radiación UV+O3, y el menos eficiente el tratamiento con ozono.
Introduction: antibiotics in the aquatic environment are an important problem due to the emergence of bacterial resistance. The long-term ecological impact on the aquatic environment is unknown. Many sources allow antibiotics to enter the environment, including wastewater treatment plants (WWTPs), agricultural runoff, hospital effluent, and landfill leachate. Objective: a study is presented that evaluates the degradation of sulfadiazine (SD), sulfamerazine (SMR) and sulfamethazine (SMT) when exposed to stress conditions due to UV radiation, ozonation and UV + ozonation. Methodology: all analyzes were performed by UV/Vis spectrophotometry after verifying by HPLC analysis that the degradation products did not significantly interfere with the absorbance of the drugs under study. Results: it was shown that the three sulfonamides are sensitive to all the degradation methods studied, the most efficient method being the combination of UV+O3 radiation, and the least efficient being the treatment with ozone.
Introdução: antibióticos no ambiente aquático são um problema importante devido ao surgimento de resistência bacteriana. O impacto ecológico a longo prazo no ambiente aquático é desconhecido. Muitas fontes permitem que antibióticos entrem no meio ambiente, incluindo estações de tratamento de águas residuais (ETEs), escoamento agrícola, efluentes hospitalares e lixiviados de aterros sanitários. Objetivo: é apresentado um estudo que avalia a degradação da sulfadiazina (SD), sulfamerazina (SMR) e sulfametazina (SMT) quando expostas a condições de estresse devido à radiação UV, ozonização e UV + ozonação. Metodologia: todas as análises foram realizadas por espectrofotometria UV/Vis após verificação por análise de HPLC que os produtos de degradação não interferiram significativamente na absorbância dos fármacos em estudo. Resultados: foi demonstrado que as três sulfonamidas são sensíveis a todos os métodos de degradação estudados, sendo o método mais eficiente a combinação da radiação UV+O3, e o menos eficiente o tratamento com Ozônio.
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