Publicado

2016-05-01

Solution thermodynamics and preferential solvation of 3-chloro-N-phenyl-phthalimide in acetone + methanol mixtures

Termodinámica de soluciones y solvatación preferencial de 3-cloro-N-fenil-ftalimida en mezclas acetona + metanol

DOI:

https://doi.org/10.15446/rcciquifa.v45n2.59941

Palabras clave:

3-Chloro-N-phenylphthalimide, solubility, solution thermodynamics, activity coefficients, preferential solvation (en)
3-cloro-N-fenil-ftalimida, solubilidad, termodinámica de soluciones, coeficiente de actividad, solvatación preferencial (es)

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Autores/as

  • Grecia Angeline del Mar Areiza Aldana Universidad Cooperativa de Colombia
  • Diego Iván Cavides Rubio Universidad Cooperativa de Colombia
  • Gerson Andrés Rodríguez Rodríguez Universidad Nacional de Colombia
  • Aleida Cuellar Lozano Universidad Cooperativa de Colombia
  • Abbas Mehrdad University of Tabriz
  • Daniel Ricardo Delgado Universidad Cooperativa de Colombia
  • Nasly Alexandra Peña Carmona Universidad Cooperativa de Colombia
The thermodynamic properties of the 3-chloro-N-phenyl-phthalimide in acetone + methanol cosolvent mixtures were obtained from solubility data report in literature. The solubility was higher in near acetone and lower in pure methanol at all temperatures studied. A non-linear plot of ∆solnH° vs. ∆solnG° shows a negative slope from pure acetone up to x1 = 0.691. Beyond this composition, a variable positive slope is obtained with the exception of mixtures with x1 = 0.121, x1 = 0.272 and x1 = 0.356 which is a not common trend in these systems. The preferential solvation of 3-chloro-N-phenyl-phthalimide by the components of the solvents was estimated by means of the inverse Kirkwood–Buff integral method, showing the 3-chloro-Nphenyl-phthalimide is preferential solvated by methanol in more polar mixtures and by acetone in less polar ones.

Las propiedades termodinámicas de 3-cloro-N-fenil-ftalimida en mezclas cosolventes acetona + metanol fueron obtenidas a partir de los datos de solubilidad reportados en la literatura. La mayor solubilidad se presentó en acetona y la menor en metanol puro en todas las temperaturas estudiadas. La grafica ΔsolnH° vs. ΔsolnG° presenta una tendencia no lineal, con una pendiente negativa desde la acetona pura hasta x1 = 0,691 a partir de esta composición hasta el metanol puro se obtiene una pendiente positiva variable con la excepción de las mezclas con x1 = 0,121, x1 = 0,272 y x1 = 0,356, la cual es una tendencia poco común en estos sistemas. La solvatación preferencial de 3-cloro-N-fenil-ftalimida por cada uno de los solventes de la mezcla se estimó por medio del método de las integrales inversas de Kirkwood-Buff mostrando que la 3-cloro-N-fenil-ftalimida se solvata preferencialmente por metanol en las mezclas más polares y por acetona en las menos polares.

Referencias

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Cómo citar

Areiza Aldana, G. A. del M., Cavides Rubio, D. I., Rodríguez Rodríguez, G. A., Cuellar Lozano, A., Mehrdad, A., Delgado, D. R., & Peña Carmona, N. A. (2016). Termodinámica de soluciones y solvatación preferencial de 3-cloro-N-fenil-ftalimida en mezclas acetona + metanol. Revista Colombiana De Ciencias Químico-Farmacéuticas, 45(2), 256-274. https://doi.org/10.15446/rcciquifa.v45n2.59941

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