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Uso de antidepressivos e percepção de saúde entre adultos de 40 anos ou mais: estudo longitudinal.
Antidepressive use and self-rated health among adults of 40 years and older: longitudinal study.
Uso de antidepresivos y percepción de la salud en adultos de 40 años o más: un estudio longitudinal.
DOI:
https://doi.org/10.15446/rcciquifa.v49n1.85776Keywords:
Antidepressivos, autopercepção de saúde, estudo longitudinal (pt)Antidepressants, Self-Rated Health, longitudinal study (en)
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Os efeitos dos antidepressivos sobre a qualidade de vida dos usuários ainda é controverso. O objetivo do estudo foi verificar a relação entre o uso de antidepressivos e a autopercepção de saúde em população de 40 anos ou mais. Trata-se de um estudo longitudinal, de base populacional, em município de médio porte no Brasil com coleta de dados em 2011 e 2015. A variável dependente foi a autopercepção da saúde (2015) e a independente foi a utilização de medicamentos antidepressivos, categorizada em “usavam somente em 2011”, “usavam somente em 2015”, “usavam em 2011 e 2015” e “não usavam”. A associação entre o uso de antidepressivos e autopercepção de saúde foi verificada pela Regressão de Poisson com variância robusta. Fizeram parte do estudo 885 pessoas. A autopercepção negativa da saúde esteve presente em 44% da população estudada. A prevalência do uso de antidepressivos foi 17,6% em 4 anos. O uso de antidepressivos esteve associado à autopercepção negativa da saúde para os indivíduos que estavam em uso somente no ano de 2015 na população geral (RP 1,082; IC 95% 1,004-1,166). Não foi verificada relação entre uso antidepressivos e autopercepção da saúde, salvo para os que utilizavam antidepressivos apenas em 2015.
References
R.C. Kessler, The costs of depression, Psychiatr. Clin. North Am., 35, 1-14 (2012).
M. Chiu, M. Lebenbaum, J. Cheng, C. de Oliveira, P. Kurdyak, The direct healthcare costs associated with psychological distress and major depression: A population-based cohort study in Ontario, Canada, PLoS One, 12(9), e0184268 (2017).
WHO, Global Burden of Disease Study 2017, 2017, Disponível em: http://www.healthdata.org/sites/default/files/files/policy_report/2019/GBD_2017_Booklet.pdf. Acessado em: outubro de 2019.
S.G. Hofmann, J. Curtiss, J.K. Carpenter, S. Kind, Effect of treatments for depression on quality of life: a meta-analysis, Cogn. Behav. Ther., 46, 265-86 (2017).
G. Lewis, L. Duffy, A. Ades, R. Amos, R. Araya, S. Brabyn, et al., The clinical effectiveness of sertraline in primary care and the role of depression severity and duration (PANDA): A pragmatic, double-blind, placebo-controlled randomised trial, Lancet Psychiatry, 6(11), 903-914 (2019).
R. Tamblyn, D.W. Bates, D.L. Buckeridge, W. Dixon, A. J. Forster, N. Girard, et al., Multinational comparison of new antidepressant use in older adults: a cohort study, BMJ Open, 9(5), e027663 (2019).
N. Aarts, R. Noordam, A. Hofman, H. Tiemeier, B.H. Stricker, L.E. Visser, Self-reported indications for antidepressant use in a population-based cohort of middle-aged and elderly, Int. J. Clin. Pharm., 38(5), 1311-1317 (2016).
M. Rotermann, C. Sanmartin, D. Hennessy, M. Arthur, Prescription medication use by Canadians aged 6 to 79, Heal Reports, 25(6), 3-9 (2014).
A. Gelenberg, M. Freeman, J.C. Markowitz, J.F. Rosembaum, M.E. Thase, M.H. Trivedi, et al., Practice guideline for adult major depressive disorder, Am. J. Psychiatry, 167, 1-152 (2010).
A. J. Rush, M.H. Trivedi, S.R. Wisniewski, J.W. Stewart, A.A. Nierenberg, M.E. Thase ME, et al., Bupropion-SR, sertraline, or venlafaxine-XR after failure of SSRIs for depression, N. Engl. J. Med., 23, 1231-1242 (2006).
C. Han, S.M. Wang, M. Kato, S.J. Lee, A.A. Patkar, P.S. Masand, et al., Second-generation antipsychotics in the treatment of major depressive disorder: current evidence, Expert Rev. Neurother., 13, 851-870 (2013).
C. Barbui, A. Cipriani, V. Patel, J.L. Ayuso-Mateos, M. van Ommeren, Efficacy of antidepressants and benzodiazepines in minor depression: systematic review and meta-analysis, Br. J. Psychiatry, 198, 11-16 (2011).
A. Cipriani, T.A. Furukawa, G. Salanti, A. Chaimani, L.Z. Atkinson, Y. Ogawa, et al., Comparative efficacy and acceptability of 21 antidepressant drugs for the acute treatment of adults with major depressive disorder: a systematic review and network meta-analysis, Lancet, 391, 1357-1366 (2018).
S. Leucht, B. Helfer, G. Gartlehner, J.M. Davis, How effective are common medications: a perspective based on meta-analyses of major drugs, BMC Med., 13, 253 (2015).
Y.A. Dombrovski, E.J. Lenze, M.A. Dew, B.H. Mulsant, B.G. Pollock, P.R. Houck, et al., Maintenance treatment for old-age depression preserves health-related quality of life: A randomized, controlled trial of paroxetine and interpersonal psychotherapy, J. Am. Geriatr. Soc., 55, 1325-1332 (2007).
A. Dzevlan, R. Redzepagic, M. Hadzisalihovic, A. Curevac, E. Masic, E. Gelo, et al., Quality of Life Assessment in Antidepressant Treatment of Patients with Depression and/or Anxiety Disorder, Mater Socio Medica, 31, 14 (2019).
R. Mago, A. Fagiolini, E. Weiller, C. Weiss, Healthcare professionals’ perceptions on the emotional impact of having an inadequate response to antidepressant medications: survey and prospective patient audit, Ann. Gen. Psychiatry, 17, 20 (2018).
R. Mago, A. Fagiolini, E. Weiller, C.Weiss, Understanding the emotions of patients with inadequate response to antidepressant treatments: results of an international online survey in patients with major depressive disorder, BMC Psychiatry, 18, 33 (2018).
W.W. Ishak, J.M. Greenberg, K. Balayan, N. Kapitanski, J. Jeffrey, H. Fathy, et al., Quality of life: The ultimate outcome measure of interventions in major depressive disorder, Harv. Rev. Psychiatry, 19, 229-239 (2011).
A. Nishi, I. Kawachi, K. Shirai, H. Hirai, S. Jeong, K. Kondo K, Sex/gender and socioeconomic differences in the predictive ability of self-rated health for mortality, PLoS One, 7, 1-7 (2012).
C. Bardage, D. Isacson, N.L. Pedersen, Self-rated health as a predictor of mortality among persons with cardiovascular disease in Sweden, Scand. J. Public Health, 29, 13-22 (2001).
K. B. DeSalvo, N. Bloser, K. Reynolds, J. He, P. Muntner, Mortality prediction with a single general self-rated health question, J Gen Intern Med, 21, 267-75 (2006).
L. Mewton, G. Andrews, Poor self-rated health and its associations with somatisation in two Australian national surveys, BMJ Open, 3, 1-8 (2013).
T.L. Vie, K.O. Hufthammer, T.L. Holmen, E. Meland, H.J. Breidablik, Is self-rated health in adolescence a predictor of prescribed medication in adulthood? Findings from the Nord Trøndelag Health Study and the Norwegian Prescription Database, SSM-Popul. Heal., 4, 144-152 (2018).
E. von Elm, D.G. Altman, M. Egger, S.J. Pocock, P.C. Gøtzsche, J.P. Vandenbroucke, The Strengthening the Reporting of Observational Studies in Epidemiology (STROBE) statement: guidelines for reporting observational studies, Lancet, 370, 1453-1457 (2007).
R.K.T. de Souza, M.S.S. Bortoletto, M.R. Loch, A.D. González, T. Matsuo, M.A.S. Cabrera, et al., Prevalência de fatores de risco cardiovascular em pessoas com 40 anos ou mais de idade, em Cambé, Paraná (2011): estudo de base populacional. Epidemiol. Serviços Saúde, 22, 435-444 (2013).
WHO, ATC/DDT Index 2019, 2019. Disponível em: https://www.whocc.no/atc_ddd_index/. Acessado em: outubro 2019.
Sociedade Brasileira de Cardiologia, Sociedade Brasileira de Hipertensão, Sociedade Brasileira de Nefrologia, VI Diretrizes Brasileiras de Hipertensão, Arq. Bras. Cardiol., 95, 1-51 (2010).
A.L.B. Pavão, G.L. Werneck, M.R. Campos, Autoavaliação do estado de saúde e a associação com fatores sociodemográficos, hábitos de vida e morbidade na população: um inquérito nacional, Cad. Saude Publica, 29, 723-734 (2013).
S.C. Confortin, M.W.C. Giehl, D.L. Antes, I.J.C. Schneider IJC, E. Orsi E, Autopercepção positiva de saúde em idosos: estudo populacional no Sul do Brasil, Cad. Saude Publica, 31, 1049-1060 (2015).
G. Cavalcanti, M. Doring, M. Rodrigues Portella, E.C. Bortoluzzi, A. Mascarelo, M.P. Dellani, Multimorbidade associado à polifarmácia e autopercepção negativa de saúde, Ver. Bras. Geriatr. Gerontol., 20, 635-643 (2017).
W.C. Yang, C.H. Lin, F.C. Wang, M.J. Lu, Factors related to the improvement in quality of life for depressed inpatients treated with fluoxetine, BMC Psychiatry, 17, 1-9 (2017).
R.W. Lam, S.V. Parikh, R. Ramasubbu, E.E. Michalak, E.M. Tam, A. Axler, et al., Effects of combined pharmacotherapy and psychotherapy for improving work functioning in major depressive disorder, Br. J. Psychiatry, 203, 358-365 (2013).
R.L. Knoth, S.C. Bolge, E. Kim, Q.V. Tran, Effect of inadequate response to treatment in patients with depression, Am. J. Manag. Care, 16, 188-196 (2010).
C.M.M. Garcias, R.T. Pinheiro, G.D.L. Garcias, B.L. Horta, C.B. Brum, Prevalência e fatores associados ao uso de antidepressivos em adultos de área urbana de Pelotas, Rio Grande do Sul, Brasil, em 2006, Cad. Saude Publica, 24, 1565-1571 (2008).
T.J. Moore, D.R. Mattison, Adult utilization of psychiatric drugs and differences by sex, age, and race, JAMA Intern. Med., 177, 274 (2017).
I. Gullich, S.M.S. Duro, J.A. Cesar, Depressão entre idosos: um estudo de base populacional no Sul do Brasil, Ver. Bras. Epidemiol., 19, 691-701 (2016).
M.R. Gualano, F. Bert, A. Mannocci, G. La Torre, P. Zeppegno, R. Siliquini R, Consumption of antidepressants in Italy: Recent trends and their significance for public health, Psychiatr. Serv., 65, 1226-1231 (2014).
A. I. de Loyola Filho, E. Castro-Costa, J.O.A. Firmo, S.V. Peixoto, Trends in the use of antidepressants among older adults: Bambuí Project, Rev. Saude Publica, 48, 857-865 (2014).
M. Alduhishy, The overprescription of antidepressants and its impact on the elderly in Australia, Trends Psychiatry Psychother., 23, 241-243 (2018).
M.N.R. Pande, P.D. de Amarante, R. Whitaker, Anatomia de uma epidemia: pílulas mágicas, drogas psiquiátricas e o aumento assombroso da doença mental, Saúde em Debate, 41, 1233-1235 (2017).
B. Mars, J. Heron, D. Kessler, N.M. Davies, R.M. Martin, K.H. Thomas, et al., Influences on antidepressant prescribing trends in the UK: 1995-2011, Soc. Psychiatry Psychiatr. Epidemiol., 24, 193-200 (2017).
P.F.M. Verhaak, D. de Beurs, P. Spreeuwenberg, What proportion of initially prescribed antidepressants is still being prescribed chronically after 5 years in general practice? A longitudinal cohort analysis, BMJ Open, 9, e024051 (2019).
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