Publicado

2006-07-01

Replicación del Herpesvirus equino y su asociación con la patogénesis molecular

Palabras clave:

EHV, genoma, glicoproteína, ORF, replicación (es)

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Autores/as

  • Julián Ruiz Sáenz Universidad Nacional de Colombia - Sede Bogotá. Grupo lnmunovirología - BIOGÉNESIS
  • Silvio Urcuqui-Inchima Corporación Ciencias Básicas Biomédicas, Universidad de Antioquia, Medellín, Colombia.
El herpesvirus equino (EHV) es uno de los patógenos virales de mayor importancia en la industria equina mundial, debido a las grandes pérdidas económicas que acarrea. La enfermedad comúnmente asociada con el EHV se denomina rinoneumonitis equina y se caracteriza por ser una infección primaria del tracto respiratorio superior, que progresa a través de la mucosa; puede causar aborto en los últimos meses de gestación, muerte perinatal de potros, mortinatos y mieloencefalitis. La infección productiva es seguida por un estado de latencia viral, etapa en la cual el animal no presenta ningún signo clínico de enfermedad y no hay replicación viral. Bajo una situación de estrés, el virus puede reactivarse y caballos infectados infectar a otros caballos sanos. En esta revisión se presenta de manera sintetizada, los principales hallazgos relacionados con la replicación viral y patogénesis molecular del EHV, relacionando además las proteínas implicadas en la regulación de la replicación del genoma, todas las glicoproteínas estructurales que han sido estudiadas hasta el momento y que son el eje central de investigación de distintos grupos en el mundo. Se discute además, la verdadera importancia de la dispersión directa célula-célula del virus, la formación de placas, el crecimiento in vitro y en algunos casos, la asociación con la patogénesis, bien sea en un modelo animal o en el hospedero natural.

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Cómo citar

APA

Ruiz Sáenz, J. y Urcuqui-Inchima, S. (2006). Replicación del Herpesvirus equino y su asociación con la patogénesis molecular. Acta Biológica Colombiana, 11(2), 3–20. https://revistas.unal.edu.co/index.php/actabiol/article/view/63281

ACM

[1]
Ruiz Sáenz, J. y Urcuqui-Inchima, S. 2006. Replicación del Herpesvirus equino y su asociación con la patogénesis molecular. Acta Biológica Colombiana. 11, 2 (jul. 2006), 3–20.

ACS

(1)
Ruiz Sáenz, J.; Urcuqui-Inchima, S. Replicación del Herpesvirus equino y su asociación con la patogénesis molecular. Acta biol. Colomb. 2006, 11, 3-20.

ABNT

RUIZ SÁENZ, J.; URCUQUI-INCHIMA, S. Replicación del Herpesvirus equino y su asociación con la patogénesis molecular. Acta Biológica Colombiana, [S. l.], v. 11, n. 2, p. 3–20, 2006. Disponível em: https://revistas.unal.edu.co/index.php/actabiol/article/view/63281. Acesso em: 28 jul. 2024.

Chicago

Ruiz Sáenz, Julián, y Silvio Urcuqui-Inchima. 2006. «Replicación del Herpesvirus equino y su asociación con la patogénesis molecular». Acta Biológica Colombiana 11 (2):3-20. https://revistas.unal.edu.co/index.php/actabiol/article/view/63281.

Harvard

Ruiz Sáenz, J. y Urcuqui-Inchima, S. (2006) «Replicación del Herpesvirus equino y su asociación con la patogénesis molecular», Acta Biológica Colombiana, 11(2), pp. 3–20. Disponible en: https://revistas.unal.edu.co/index.php/actabiol/article/view/63281 (Accedido: 28 julio 2024).

IEEE

[1]
J. Ruiz Sáenz y S. Urcuqui-Inchima, «Replicación del Herpesvirus equino y su asociación con la patogénesis molecular», Acta biol. Colomb., vol. 11, n.º 2, pp. 3–20, jul. 2006.

MLA

Ruiz Sáenz, J., y S. Urcuqui-Inchima. «Replicación del Herpesvirus equino y su asociación con la patogénesis molecular». Acta Biológica Colombiana, vol. 11, n.º 2, julio de 2006, pp. 3-20, https://revistas.unal.edu.co/index.php/actabiol/article/view/63281.

Turabian

Ruiz Sáenz, Julián, y Silvio Urcuqui-Inchima. «Replicación del Herpesvirus equino y su asociación con la patogénesis molecular». Acta Biológica Colombiana 11, no. 2 (julio 1, 2006): 3–20. Accedido julio 28, 2024. https://revistas.unal.edu.co/index.php/actabiol/article/view/63281.

Vancouver

1.
Ruiz Sáenz J, Urcuqui-Inchima S. Replicación del Herpesvirus equino y su asociación con la patogénesis molecular. Acta biol. Colomb. [Internet]. 1 de julio de 2006 [citado 28 de julio de 2024];11(2):3-20. Disponible en: https://revistas.unal.edu.co/index.php/actabiol/article/view/63281

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