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El papel de los odontólogos en la atención integral para la prevención oportuna de la osteonecrosis maxilar asociada a medicamentos
The role of dentists in comprehensive care to timely prevent medication-related osteonecrosis of the jaw
DOI:
https://doi.org/10.15446/revfacmed.v74.124504Palabras clave:
Osteonecrosis de los Maxilares Asociada a Difosfonatos, Bifosfonatos, Osteonecrosis, Atención Odontológica, Prevención Primaria (es)Bisphosphonate-Associated Osteonecrosis of the Jaw, Osteonecrosis, Bisphosphonates, Dental Care, Primary Prevention (en)
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Los primeros casos de osteonecrosis maxilar relacionada con
medicamentos (MRONJ) se reportaron en 2003 y se asociaron al uso de
bisfosfonatos.1 Desde entonces, si bien se han logrado múltiples
avances respecto a su definición, clasificación, diagnóstico y
tratamiento, también han surgido varias controversias.2
Dear Editor:
The first cases of medication-related osteonecrosis of the jaw (MRONJ) were reported in 2003 and were associated with the use of bisphosphonates.1 Since then, multiple advances have been made regarding its definition, classification, diagnosis, and treatment, but several controversies have also emerged.2
Referencias
1. Chalem M, Medina A, Sarmiento AK, Gonzalez D, Olarte C, Pinilla E, et al. Therapeutic approach and management algorithms in medication-related osteonecrosis of the jaw (MONJ): recommendations of a multidisciplinary group of experts. Arch Osteoporos. 2020;15(1). doi: 10.1007/s11657-020-00761-0. PMID: 32623599.
2. Ruggiero SL, Dodson TB, Aghaloo T, Carlson ER, Ward BB, Kademani D. American Association of Oral and Maxillofacial Surgeons’ Position Paper on Medication-Related Osteonecrosis of the Jaws—2022 Update. J Oral Maxillofac Surg. 2022;80(5):920-43. doi: 10.1016/j.joms.2022.02.008. PMID: 35300956.
3. Ruan HJ, Chen H, Hou JS, An JG, Guo YX, Liu B, et al. Chinese expert consensus on the diagnosis and clinical management of medication-related osteonecrosis of the jaw. J Bone Oncol. 2024;49:100650. doi: 10.1016/j.jbo.2024.100650. PMID: 39651419; PMCID: PMC11621599.
4. Bedogni A, Mauceri R, Fusco V, Bertoldo F, Bettini G, Di Fede O, et al. Italian position paper (SIPMO‐SICMF) on medication‐related osteonecrosis of the jaw (MRONJ). Oral Dis. 2024;30(6):3679-709. doi: 10.1111/odi.14887. PMID: 38317291.
5. Mauceri R, Coniglio R, Abbinante A, Carcieri P, Tomassi D, Panzarella V, et al. The preventive care of medication-related osteonecrosis of the jaw (MRONJ): a position paper by Italian experts for dental hygienists. Support Care Cancer. 2022;30(8):6429-40. doi: 10.1007/s00520-022-06940-8. PMID: 35292850; PMCID: PMC9213300.
6. Radaic A, Kapila YL. The oralome and its dysbiosis: New insights into oral microbiome-host interactions. Comput Struct Biotechnol J. 2021;19:1335-60. doi: 10.1016/j.csbj.2021.02.010. PMID: 33777334; PMCID: PMC7960681.
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Derechos de autor 2026 El(Los) autor(es).

Esta obra está bajo una licencia internacional Creative Commons Atribución 4.0.
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