Volumen 64, Número 3 Revista de la Facultad de Medicina

Publicado

2016-07-01

Fulminant gas gangrene in an adolescent with immunodeficiency. Case report and literature review

Gangrena gaseosa fulminante en adolescente con inmunodeficiencia. Reporte de caso y revisión de la literatura

Palabras clave:

Gas Gangrene, Infection, Immunodeficiency, Subcutaneous Emphysema, Histiocytosis (en)
Gangrena gaseosa, Inmunodeficiencia, Histiocitosis (es)

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Autores/as

  • Edna Karina García Universidad Nacional de Colombia - Sede Bogotá - Faculty of Medicine - Department of Pediatrics - Bogotá, D.C. - Colombia.
  • Pedro Alberto Sierra Universidad Nacional de Colombia - Sede Bogotá - Faculty of Medicine - Department of Pediatrics - Bogotá, D.C. - Colombia. Fundación Hospital de La Misericordia - Emergency Department - Bogotá, D.C. - Colombia.
  • Omar Quintero-Guevara Universidad Nacional de Colombia - Sede Bogotá - Faculty of Medicine - Department of Pediatrics - Bogotá, D.C. - Colombia. Fundación Hospital de La Misericordia - Emergency Department - Bogotá, D.C. - Colombia.
  • Lina Jaramillo Universidad Nacional de Colombia - Bogotá Campus - Faculty of Medicine - Department of Pathology - Bogotá, D.C. - Colombia.
Immunity defects are important predisposing factors to aggressive infections with high risk of mortality. The case of a teenager with a history of immunodeficiency, who developed gas gangrene infection originated in the left lower limb is reported here. The disease progressed in less than 24 hours, developed systemic involvement and led to multiple organ failure and death. Pathophysiological aspects and features of the agent are reviewed here, highlighting the importance of high index of clinical suspicion and immediate handling.

Los defectos de la inmunidad constituyen un importante factor predisponente a las infecciones agresivas de alto riesgo de mortalidad.

Se presenta el caso de un adolescente con antecedente de inmunodeficiencia, quien de forma rápida desarrolla infección del tipo gangrena gaseosa. La infección inicia en miembro inferior izquierdo y en menos de 24 horas desarrolla compromiso sistémico con falla orgánica múltiple y el paciente fallece.

Se revisan los aspectos fisiopatológicos y las características del agente causal, resaltando la importancia del diagnóstico y tratamiento oportuno y temprano.

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