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Prevalence of defining malignancies in adult patients with HIV/AIDS in the National Cancer Institute of Colombia. 2007-2014
Prevalencia de neoplasias en pacientes adultos con VIH/sida del Instituto Nacional de Cancerología de Colombia. 2007-2014
Palabras clave:
HIV, Acquired Immunodeficiency Syndrome, Malignances, Highly Active Antiretroviral Therapy, Colombia (en)VIH, Síndrome de inmunodeficiencia adquirida, Neoplasias, Terapia antirretroviral altamente activa, Colombia (es)
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Introduction: The widespread use of antiretroviral therapy has increased the survival rates of patients infected with human immunodeficiency virus (HIV) and, in consequence, the prevalence of both defining and non-defining cancers. In Colombia, information in this regard is unknown.
Objective: To determine the prevalence of defining malignancies in adult patients with HIV treated at the National Cancer Institute over a seven-year period.
Materials and methods: Descriptive study involving adult patients diagnosed with HIV and cancer. Sociodemographic variables, CD4 count, viral load and antiretroviral therapy were analyzed by establishing association measures with the presence of defining malignancies.
Results: 139 patients with confirmed HIV and cancer diagnosis were found; 84.2% were men. The age range was between 18 and 71 years, with a mean of 41.3±10.9 years. Defining cancers corresponded to 65.5% of the cases, the most frequent being non-Hodgkin lymphoma. The remaining percentage corresponded to non-defining cancers, mainly anal cancer and Hodgkin’s lymphoma.
Conclusion: Despite the global trend, the population studied here shows predominance of defining cancers, which, like HIV, continue to be detected at a late stage.
Introducción. El uso de la terapia antirretroviral ha aumentado la supervivencia de los pacientes con virus de inmunodeficiencia humana (VIH) y, como consecuencia, la prevalencia de cánceres definitorios y no definitorios. En Colombia no se conoce información al respecto.
Objetivo. Determinar la prevalencia de neoplasias definitorias en pacientes adultos con VIH del Instituto Nacional de Cancerología en un período de 7 años.
Materiales y métodos. Se realizó un estudio descriptivo que incluyó pacientes adultos con diagnóstico de VIH y cáncer. Se analizaron variables sociodemográficas, conteo de CD4, carga viral y tratamiento antirretroviral. Se establecieron medidas de asociación entre las últimas tres variables y la aparición de neoplasias definitorias.
Resultados. Se estudiaron 139 pacientes con diagnóstico de VIH y cáncer, 84.2% de los cuales eran hombres. El rango de edad osciló entre 18 y 71 años con una media de 41.3±10.9 años. Las neoplasias definitorias se presentaron en 65.5% de los casos; la más frecuente fue el linfoma no Hodgkin. El porcentaje restante correspondió a neoplasias no definitorias, en su mayoría, cáncer anal y linfoma de Hodgkin.
Conclusión. Pese a la tendencia mundial, en la población evaluada hay preponderancia de neoplasias definitorias, las cuales —al igual que el VIH— siguen detectándose de forma tardía.
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Derechos de autor 2017 Revista de la Facultad de Medicina
Esta obra está bajo una licencia Creative Commons Reconocimiento 3.0 Unported.
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