Efecto de la crioterapia en la articulación tibiotarsiana en el área de sección transversa de los músculos tibial anterior y sóleo en ratas
Effects of cryotherapy on the tibiotarsal joint in the cross-sectional area of rat tibialis anterior and soleus muscles
DOI:
https://doi.org/10.15446/revfacmed.v68n4.77367Palabras clave:
Crioterapia, Rehabilitación, Inflamación (es)Cryotherapy, Rehabilitation, Inflammation (en)
Introducción. La crioterapia se usa para tratar la inflamación articular aguda, sin embargo su efecto sobre el músculo relacionado con la articulación inflamada aún no ha sido estudiado.
Objetivo. Evaluar el efecto de la crioterapia sobre la articulación tibiotarsiana en el área de sección transversa (AST) de los músculos tibial anterior (TA) y sóleo en ratas con inflamación articular aguda.
Materiales y métodos. Estudio experimental realizado en 32 ratas Wistar que fueron asignadas aleatoriamente a cuatro grupos: Control, Inflamación, Crioterapia-A y Crioterapia- B. El AST de las fibras de los músculos se midió 72 horas después de haberse iniciado el experimento.
Resultados. En el músculo TA hubo una reducción significativa del AST de las fibras musculares en los grupos Inflamación y Crioterapia-B en comparación con el grupo Control, mientras que en el grupo Crioterapia-A no se observó una reducción significativa en dicha área al compararlo con el Control. En el caso del músculo sóleo, se observó una reducción significativa del área en todos los grupos experimentales.
Conclusión. El uso de crioterapia una vez al día por tres días atenúa el efecto atrófico de la inflamación articular aguda sobre el músculo TA, lo que confirma su importancia en el control del efecto deletéreo de la inflamación aguda sobre músculos de contracción rápida.
Introduction: Cryotherapy is used to treat acute joint inflammation, but its effect on muscles associated with the injured joint has not yet been studied.
Objective: To evaluate the effect of cryotherapy on the tibiotarsal joint in the cross-sectional area (CSA) of tibialis anterior (TA) and soleus muscles in rats with acute joint inflammation.
Materials and methods: Experimental study conducted on 32 Wistar rats that were randomly assigned to four groups: Control, Inflammation, Cryotherapy-A and Cryotherapy-B. The CSA of muscle fibers was measured 72 hours after initiating the experiment.
Results: In the case of the TA muscle, there was a significant reduction in the CSA muscle fibers in the Inflammation and Cryotherapy-B groups compared to the Control group, while no significant reduction was observed in the Cryotherapy-A group in relation to the Control group. Regarding the soleus muscle, a significant CSA reduction was observed in all experimental groups.
Conclusion: The use of cryotherapy once a day for three days attenuates the atrophic effect of acute joint inflammation on the TA muscle, confirming its importance for controlling the deleterious effects of acute inflammation on fast-twitch muscles.
Descargas
Citas
Suetta C, Aagaard P, Magnusson SP, Andersen LL, Sipilä S, Rosted A et al. Muscle size, neuromuscular activation, and rapid force characteristics in elderly men and women: effects of unilateral long-term disuse due to hip osteoarthritis. J Appl Physiol. 2007;102(2):942-8.http://doi.org/fg998b.
Palmieri RM, Ingersoll CD, Hoffman MA, Cordova ML, Porter DA, Edwards JE, et al. Arthrogenic muscle response to a simulated ankle joint effusion. Br J Sports Med. 2004;38(1):26-30.http://doi.org/bc8x5q.
Hopkins JT, Ingersoll CD, Edwards J, Klootwyk TE. Cryotherapy and transcutaneous electric neuromuscular stimulation decrease arthrogenic muscle inhibition of the vastus medialis after knee joint effusion. J Athl Train. 2001;37(1):25-31.
Williams GN, Barrance PJ, Snyder-Mackler L, Buchanan TS. Altered quadriceps control in people with anterior cruciate ligament deficiency. Med Sci Sport Exer. 2004;36(7):1089-97. http://doi.org/d48bjs.
Akima H, Furukawa T. Atrophy of thigh muscles after meniscal lesions and arthoscopic partial menisectomy. Knee Surg Sports Traumatol Arthrosc. 2005;13(6):632-37. http://doi.org/dr8gm2.
Stockmar C, Lill H, Trapp A, Josten C, Punkt K. Fibre type related changes in the metabolic profile and fibre diameter of human vastus medialis muscle after anterior cruciate ligament rupture. Acta Histochem. 2006;108(5):335-42.http://doi.org/fwwrcp.
Palmieri RM, Tom JA, Edwards JE, Weltman A, Saliba EN, Mistry DJ, et al. Arthrogenic muscle response induced by an experimental knee joint effusion is mediated by pre- and post-synaptic spinal mechanisms. J Electromyogr Kinesiol. 2004;14(6):631-40. http://doi.org/cxk7dz.
Ramírez C, Russo TL, Sandoval MC, Dentillo AA, Silav-Couto MA, Quagliotti-Durigan JL, et al. Joint inflammation alters gene and protein expression and leads to atrophy in the tibialis anterior of rats. Am J Phys Med Rehabil. 2011;90(1):938-49. http://doi.org/d2799p.
Ramírez C, Russo TL, Delfino G, Peviani SM, Alcântara C, Salvini TF. Effect of tibiotarsal joint inflammation on gene expression and cross-sectional area in rat soleus muscle. Braz J Phys Ther. 2013;17(3):244-54. http://doi.org/d6nz.
Lieber R. Skeletal muscle structural, function, & plasticity. 3rd ed. Philadelphia: Lippincott Williams & Wilkins; 2010.
Malanga GA, Yan N, Stark J. Mechanisms and efficacy of heat and cold therapies for musculoskeletal injury. Postgrad Med. 2014;127(1):57-65. 10.1080/00325481.2015.992719..
Vieira-Ramos G, Pinheiro CM, Mesa SP, Delfino GB, Marqueti RC, Salvini TF, et al. Cryotherapy Reduces Inflammatory Response Without Altering Muscle Regeneration Process and Extracellular Matrix Remodeling of Rat Muscle. Sci Rep. 2016;6:18525. http://doi.org/f9fqwz.
Siqueira AF, Vieira A, Vieira-Ramos V, Marqueti RC, Salvini TF, Puntel GO, et al. Multiple cryotherapy applications attenuate oxidative stress following skeletal muscle injury. Redox Rep. 2017;22(6):323-9. http://doi.org/d6vh.
Oakley ET, Pardeiro RB, Powell JW, Millar AL. The effects of multiple daily applications of ice to the hamstrings on biochemical measures, signs, and symptoms associated with exercise-induced muscle damage. J Strength Cond Res. 2013;27(10):2743-51. http://doi.org/d6vj.
Wang Y, Huang C, Cao Y, Han JS. Repeated administration of low dose ketamine for the treatment of monoarthritic pain in the rat. Life Sci. 2000;67(3):261-7. http://doi.org/b293fh.
Omote K, Kawamata T, Nakayama Y, Yamamoto H, Kawamata M, Namiki A. Effects of a Novel Selective Agonist for Prostaglandin Receptor Subtype EP4 on Hyperalgesia and Inflammation in Monoarthritic Model. Anesthesiology. 2002;97(1):170-6. http://doi.org/bk9z87.
National Academy of Sciences Guide for the Care and Use of Laboratory Animals. 8th ed. Washingtong D.C.: National Academies Press; 2011.
World Medical Association (WMA). WMA Declaration of Helsinki – Ethical principles for medical research involving human subjects. Fortaleza: 64th WMA General Assembly; 2013.
Colombia. Ministerio de Salud. Resolución 8430 de 1993 (octubre 4): Por la cual se establecen las normas científicas, técnicas y administrativas para la investigación en salud. Bogotá D.C.; octubre 4 de 1993.
Sánchez-Martínez Y, Matiz-Gonzáles M, Mora-Gómez L, Santander-Celi C, Ramírez-Ramírez C. Rehabilitación en la inhibición muscular artrogénica: revisión sistemática. Rev. Colomb. Rehabil. 2017;16(2):16-23. http://doi.org/d6t8.
Hopkins JT. Knee joint effusion and cryotherapy alter lower chain kinetics and muscle activity. J Athl Train. 2006;41(2), 177-84.
Klykken LW, Pietrosimone BG, Kim KM, Ingersoll CD, Hertel J. Motor-neuron pool excitability of the lower leg muscles after acute lateral ankle sprain. J Athl Train. 2011;46(3),263-9. http://doi.org/d6vk.
Oliveira NML, Rainero EP, Salvini TF. Three intermittent sessions of cryotherapy reduce the secondary muscle injury in skeletal muscle of rat. J Sports Sci Med. 2006;5(2):228-34.
Hopkins J, Ingersoll CD, Edwards J, Klootwyk TE. Cryotherapy and transcutaneous electric neuromuscular stimulation decrease arthrogenic muscle inhibition of the vastus medialis after knee joint effusion. J Athl Train. 2001;37(1):25-31.
Rice DA, McNair PJ, Lewis GN, Dalbeth N. Quadriceps arthrogenic muscle inhibition: the effects of experimental knee joint effusion on motor cortex excitability. Arthritis Res Ther. 2014;16(6):502-8. http://doi.org/gb92gr.
Palmieri-Smith RM, Leonard-Frye JL, Garrison CJ, Weltman A, Ingersoll CD. Peripheral joint cooling increases spinal reflex excitability and serum norepinephrine. Int J Neurosci. 2007;117(2):229-42. http://doi.org/dgbgm6.
Hopkins JT, Stencil R. Ankle cryotherapy facilitates soleus function. J Orthop Sports Phys Ther. 2002;32(12):622-7. http://doi.org/d6v7.
Rakus D, Gizak A, Deshmukh A, Wiśniewski JR. Absolute Quantitative profiling of the Key Metabolic Pathways in Slow and Fast Skeletal Muscle. J Proteome Res. 2015;14(3):1400-11. http://doi.org/f69sr5.
Okamoto T, Machida S. Changes in FOXO and proinflammatory cytokines in the late stage of immobilized fast and slow muscle atrophy. Biomed Res. 2017;38(6):331-42. http://doi.org/d6v8.
Wang Y, Pessin JE. Mechanisms for fiber-type specificity of skeletal muscle atrophy. Curr Opin Clin Nutr Metab Care. 2013;16(3):243-50. http://doi.org/d6v9.
Pérez M, Lucia A, Rivero JL, Serrano AL, Calbet JA, Delgado MA, et al. Effects of transcutaneous short-term electrical stimulation on M. vastus lateralis characteristics of healthy young men. Pflugers Arch. 2002;443(5-6):866-74. http://doi.org/cv4fgr.
Sillen MJ, Franssen FM, Gosker HR, Wouters EFM, Spruit MA. Metabolic and structural changes in lower-limb skeletal muscle following neuromuscular electrical stimulation: a systematic review. PLoS One. 2013;8(9):e69391. http://doi.org/d6wc.
Licencia
Derechos de autor 2020 Revista de la Facultad de Medicina

Esta obra está bajo una licencia Creative Commons Reconocimiento 3.0 Unported.
-








