Publicado

2010-01-01

Influenza A H1N1 de origen porcino: métodos diagnósticos

Influenza A H1N1 swine origin: diagnostic methods

Palabras clave:

influenza humana (gripe humana), subtipo H1N1 del virus de la influenza A, infección, virología. (es)
influenza, human, influenza A virus, H1N1 subtype, infection, virology. (en)

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Autores/as

  • Manuel Antonio Vargas-Córdoba Profesor Titular Departamento de Microbiología. Facultad de Medicina, Universidad Nacional de Colombia, Bogotá.
El diagnóstico de la infección por virus influenza reposa sobre técnicas virológicas directas e indirectas. Las diferentes pruebas diagnósticas poseen niveles de sensibilidad y especificidad variables que dependen en gran parte de las características genéticas y antigénicas del virus circulante. En el caso de la aparición de una nueva variante viral las pruebas disponibles en el mercado deben ser validadas para comprobar su eficiencia de detección para el nuevo virus. En caso de baja sensibilidad y especificidad, las pruebas deben ajustarse con el fin de mejorar su poder de detección del nuevo agente. Existen múltiples pruebas diagnósticas que presentan cada una sus ventajas y limitaciones y su selección dependerá de las condiciones específicas de cada laboratorio diagnóstico.

The diagnosis of infection by influenza viruses relays on direct and indirect virologic techniques. Different diagnostic tests have variable sensitivities and specificities depending to a large extent on the genetic and antigenic features of the circulating virus. When a new viral variant appears, commercially available tests must be validated in order to verify their performance at detecting the new virus.

If a low sensitivity or specificity is found, tests must be adjusted in order to improve their detection power for the new agent. There are multiple diagnostic tests, each one with its own advantages and limitations; so the selection of a test will depend on the specific conditions of a particular diagnostic laboratory.

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Cómo citar

Vargas-Córdoba, M. A. (2010). Influenza A H1N1 de origen porcino: métodos diagnósticos. Revista De La Facultad De Medicina, 58(1), 44-59. https://revistas.unal.edu.co/index.php/revfacmed/article/view/14360

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Derechos de autor 2010 Revista de la Facultad de Medicina

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Esta obra está bajo una licencia Creative Commons Reconocimiento 3.0 Unported.

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