Publicado

2011-01-01

Los desórdenes del lenguaje: de las neurociencias a la neurorehabilitación

Language disorders: from neuroscience to neurorehabilitation

Palabras clave:

lenguaje, afasia, neurociencias, rehabilitación. (es)

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Autores/as

  • Janeth Hernández Jaramillo Profesora principal de carrera y miembro del Grupo de Investigación Rehabilitación e Inclusión Social de la Persona con Discapacidad de la Escuela de Medicina y Ciencias de la Salud de la Universidad del Rosario.
  • Manuel Guillermo Uribe Granja Facultad de Medicina Universidad Colegio Mayor de Nuestra Señora del Rosario- Hospital de San José. Coordinador de la Línea de Neurotoxicología del Grupo de Neurociencias- NEUROS- de la Escuela de Medicina y Ciencias de la Salud de la Universidad del Rosario.
El propósito de este texto es revisar una serie de referentes concluyentes de la investigación en neurociencias y derivar un fundamento para la intervención en los desórdenes de la comunicación con origen neurológico. La evidencia sobre los desenlaces de recuperación de las alteraciones neurocomunicativas señala que es difícil predecir, a largo plazo, la funcionalidad de un paciente con lesión cerebral. A pesar de que el curso de la recuperación de los desórdenes de origen neurológico del habla y el lenguaje es diferente atendiendo a la naturaleza, extensión y localización de la lesión, existe evidencia que cerca del 80% de los pacientes con daño cerebral adquirido muestran mejoría importante entre las 10 y 22 semanas posteriores a la lesión. El patrón de recuperación no permite predecir los progresos en razón del tiempo; dado que diversos tipos de plasticidad tienen lugar en diferentes estadios de las lesiones neurológicas. La evidencia neurocientífica señala la existencia de variables relacionadas con la neurorehabilitación y la recuperación de las alteraciones neurocomunicativas, susceptibles de ser manipuladas tales como: el tiempo, la intensidad, la cantidad del tratamiento y otras variables de la intervención, así como las propias condiciones neurales; de la misma manera se han identificado variables de resultado del proceso de neurorehabilitación relacionadas con la adquisición, la generalización, el mantenimiento, la interferencia y los efectos de la neurobiología que soporta los comportamientos cognoscitivolingüísticos.
This manuscript has been aimed at reviewing a series of conclusive referents in neuroscience research thereby deriving a basis for intervention in neurological communication disorders. Evidence regarding recovery outcomes following alterations in neurocommunication suggests that it is difficult to predict the long-term functionality of a patient suffering a cerebral lesion. In spite of the course of recovery regarding speech and language in neurological disorders being different depending on the nature, extent and location of the lesion, some evidence suggests that around 80% of patients suffering cerebral damage have shown important improvement 10 to 22 weeks after such lesion. The recovery pattern does not allow progress to be predicted regarding time given that different types of plasticity dominate during neurological lesions' different stages. Neuroscientific evidence has pointed to the existence of variables related to neurorehabilitation and the recovery of neurocommunication alterations which are susceptible to being manipulated such as time, intensity, amount of treatment and other variables regarding intervention, as well as the neural conditions themselves. Likewise, variables have been identified as a result of neurorehabilitation related to acquisition, generalization, maintenance, interference and the effects of neurobiology supporting cognitive-linguistic behaviour.

Referencias

Benson DF, Ardilla A. Brain damage in aphasia. In: Benson DF, Ardilla A, eds. Aphasia. A clinical perspective. New York Oxford University Press. 1996: 61-87.

Basso A. How intensive/prolonged should an intensive/prolonged treatment be? Aphasiology. 2005; 19: 975-984.

Basso A, Capitani E, Vignolo LA. Influence of rehabilitation on language skills in aphasic patients. A controlled study. Arch Neurol. 1979; 36: 190-196.

Wertz RT, Collins MJ, Weiss D, Kurtzke JF, Friden T, Brookshire RH, et al. Veterans Administration cooperative study on aphasia: a comparison of individual and group treatment. J Speech Hear Res. 1981; 24: 580-594.

Wertz RT, Weiss DG, Aten JL, Brookshire RH, García-Buñuel L, Holland AL, et al. Comparison of clinic, home, and deferred language treatment for aphasia. A Veterans Administration Cooperative Study. Arch Neurol. 1986; 43: 653-658.

Lendrem W, Lincoln NB. Spontaneous recovery of language in patients with aphasia between 4 and 34 weeks after stroke. J Neurol Neurosurg Psychiatry. 1985; 48: 743-748.

Porch BE, Collins M, Wertz RT, Friden TP. Statistical prediction of change in aphasia. J Speech Hear Res. 1980; 23: 312-321.

Goodglass H, Wingfield A. Selective preservation of a lexical category in aphasia: dissociations in comprehension of body parts and geographical place names following focal brain lesion. Memory. 1993; 1: 313-328.

Shewan C, Kertesz A. Effects of speech and language treatment and recovery from aphasia. Brain and language. 1984; 2: 272-299.

Beeson PM, Hillis AE. Comprehension and production of written words. In. R. Chapey (Ed.). Language intervention strategies in adult aphasia, Fourth Edition (pp. 572-595). Baltimore, MD: Lippencott, Williams & Wilkins. 2001.

Nickels DM. Casting the discovery net too wide: defense attempts to disclose nonparty medical records in a civil action.Spec Law Dig Health Care Law. 2002; 277: 9-30.

Raymer AM, Rothi LJ. Cognitive neuropsychological approaches to assessment and treatment: Impairments of lexical comprehension and production. 2001. In R. Chapey (Ed.), Language intervention strategies in adult aphasia (4th ed., pp. 524-550). Philadelphia: Lippincott, Williams, & Wilkins.

Marshall RC. Having the courage to be competent: persons and families living with aphasia. J Commun Disord. 2002; 35: 139-152.

Thompson CK, Shapiro LP. Treating agrammatic aphasia within a linguistic framework: Treatment of Underlying Forms. Aphasiology. 2005; 9: 1021-1036.

Shisler RJ, Baylis GC, Frank EM. Pharmacological approaches to aphasia. Aphasiology, 2000; 14: 1163-1186.

Small S. A biological model of aphasia rehabilitation: Pharmacological perspectives. Aphasiology. 2004; 18: 473-492.

Bhogal SK, Teasell RW, Foley NC, Speechley MR. Community reintegration after stroke. Top Stroke Rehabil. 2003; 10: 107-129.

Bhogal SK, Teasell RW, Foley NC, Speechley MR. Quality of the stroke rehabilitation research. Top Stroke Rehabil. 2003; 10: 8-28.

Robey RR. A meta-analysis of clinical outcomes in the treatment of aphasia. J Speech Lang Hear Res. 1998; 41: 172- 187.

Robey RR. The efficacy of treatment for aphasic persons: a meta-analysis. Brain Lang. 1994; 47: 582-608.

La Pointe L. Aphasia and related disorders. 2005 (3rded.). New York. Thieme.

Murray LL, Clark HM. Neurogenic disorders of language: Theory driven clinical practice. Clifton Park, NY: Thomson Delmar Learning. 2006.

Grossman AW, Churchill JD, McKinney BC, Kodish IM, Otte SL, Greenough WT. Experience effects on brain development: possible contributions to psychopathology. J Child Psychol Psychiatry. 2003; 44: 33-63.

Kleim JA, Jones TA. Principles of experiencedependent neural plasticity: Implications for rehabilitation after brain damage. Journal of Speech, Language, and Hearing Research. 2008; 51: S225-S239.

Cappa SF, Perani D, Grassi F, Bressi S, Alberoni M, Franceschi M, et al. A PET follow-up study of recovery after stroke in acute aphasies. Brain and Language. 1997; 56: 55-67.

Thompson CK. Neuroimaging: Applications for studying aphasia. In L.L. LaPointe (Ed.), Aphasia and related disorders (pp. 19-38). New York: Thieme. 2004.

Brodal A. Self- observations and neuroanatomical considerations after at stroke. Brain. 1973; 96: 675-694.

Pataraia E, Simos PG, Castillo EM, Billingsley-Marshall RL, McGregor AL, Breier JI, et al. Reorganization of language-specific cortex in patients with lesions or mesial temporal epilepsy. Neurology. 2004; 63: 1825-1832.

Price C, Howard D, Patterson K, Warburton EA, Fristen KJ, Frackowiak RS. A functional neuroimaging description of deep dyslexic patients. Journal of Cognitive Neuroscience. 1998; 10: 303-315.

Belin P, Van Eeckhout P, Zilbovicius M, Remy P, Francois C, Guillaume S, et al. Recovery from nonfluent aphasia after melodic intonation therapy: A PET study. Neurology. 1996; 47: 1504-1511.

Papanicolaou A, Moore B, Deutsch G, Levin H, Eisenberg M. Evidence for right-hemisphere involvement in recovery from aphasia. Archives of Neurology. 1988; 45: 1025-1029.

Cooper SJ, Donald O. Hebb's synapse and learning rule: A history and commentary. Neuroscience and Biobehavioral Reviews. 2005; 28: 851-874.

Kandel ER. The molecular biology of memory storage: a dialog between genes and synapses. Biosci Rep. 2001; 5: 565-611.

Kwakkel G, Kollen B, Lindeman E. Understanding the pattern of functional recovery after stroke: facts and theories. Restor Neurol Neurosci. 2004; 22: 281-99.

Jones TA, Bury SD, Adkins-Muir DL, Luke LM, Alfred RP, Sakata JT. Importance of behavioral manipulations and measures in rat models of brain damage and brain repair. ILAR Journal. 2003; 44: 144-152.

Whishaw IQ. Loss of the innate cortical engram for action patterns used in skilled reaching send the development of behavioral compensation following motor cortex lesions in the rat. Neuropharmacology. 2000; 39: 788-805.

Hubel DH, Wiesel TN. Binocular interaction in striate cortex of kittens reared with artificial squint. Journal of Neurophysiology. 1965; 28: 1041-1059.

Pascual R, Hervias MC, Toha ME, Valero A, Figueroa HR. Purkinje cell impairment induced by early movement restriction. Biology of the Neonate. 1998; 73: 47-51.

Pulvermüller F, Berthier ML. Aphasia therapy on a neuroscience basis. Aphasiology. 2008; 22: 563-599.

Liepert J, Bauder H, Wolfgang HR, Miltner WH, Taub E, Weiller C. Treatment-induced cortical reorganisation after stroke in humans. Stroke. 2000; 31: 1210-1216.

Raymer AM, Beeson P, Holland A, Kendall D, Maher LM, Martin N, et al. Translation Research in Aphasia: From neuroscience to neurorehabilitation. J Speech Lang Hear Res. 2008; 51: S259-275.

Gonzalez Rothi LJ, Musson N, Rosenbek JC, Sapienza CM. Neuroplasticity and rehabilitation research for speech, language, and swallowing disorders. J Speech Lang Hear Res. 2008, 51: S222-224.

Woodlee MT, Schallert T. The impact of motor activity and inactivity on the brain. Current Directions in Psychological Science. 2006; 15: 203-206.

Raymer AM, Kohen FP, Saffell D. Computerised training for impairments of word comprehension and retrieval in aphasia. Aphasiology. 2006; 20: 257-268.

Pulvermüller F, Neininger B, Elbert T, Mohr B, Rockstroh B, Koebbel P, Taub E. Constraint-induced therapy of chronic aphasia after stroke. Stroke. 2001; 32: 1621-1626.

Humm JL, Kozlowski DA, James DC, Gotts JE, Schallert T. Use-dependent exacerbation of brain damage occurs during an early post-lesion vulnerable period. Brain Research. 1998; 16: 4776-4786.

Conner, J. M., Chiba, A. A., & Tuszynski, M. H. The basal forebrain cholinergic system is essential for cortical plasticity and functional recovery following brain injury. Neuron, 2005; 46, 173-179.

Salat DH, Buckner RL, Snyder AZ, Greve DN, Desikan RS, Busa E, et al. Thinning of the cerebral cortex in aging. Cerebral Cortex. 2004; 14: 721-730.

Pitcher JB, Ogston KM, Miles TS. Age and sex differences in human motor cortex input-output characteristics. J Physiol. 2003; 546: 605-13.

Churchill JD, Galvez R, Colcombe S, Swain RA, Kramer AF, Greenough WT. Exercise, experience, and the aging brain. Neurobiology of Aging. 2002; 23: 941-955.

Pascuale-Leone A, Wassermann EM, Sadato N, Hallett M. The role of reading activity on the modulation of motor cortical outputs to the reading hand in Braille readers. Annals of Neurology. 1995; 38: 910-915.

Fraser C, Power M, Hamdy S, Rothwell J, Hobday D, Hollander I, et al. Driving plasticity in human adult motor cortex is associated with improved motor function elfter brain injury. Neuron. 2002; 34: 831-840.

Boyd L, Winstein C. Explicit information interferes with implicit motor learning of both continuous and discrete movement tasks after stroke. Journal of Neurologic Physical Therapy. 2006; 30: 46-57.

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Hernández Jaramillo, J., & Uribe Granja, M. G. (2011). Los desórdenes del lenguaje: de las neurociencias a la neurorehabilitación. Revista De La Facultad De Medicina, 59(1), 56-67. https://revistas.unal.edu.co/index.php/revfacmed/article/view/20632